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Abstract：
Transitional cell carcinoma (TCC) of the ovary is a rare subtype of epithelial ovarian tumours defined as a tumour composed of epithelial elements, histologically resembling urothelium and its neoplasms. Ovarian metastases from primary urinary tract carcinomas are rare. The differential diagnosis of primary TCC of the ovary versus metastatic bladder TCC is challenging because of histological similarity. We present the case of a 49-year-old premenopausal woman who was initially diagnosed with non-invasive papillary urothelial carcinoma of bladder (NIPUC) and after 2 years with a synchronous TCC of the ovary while being investigated for suspected relapse. She underwent a radical cystectomy, total hysterectomy, bilateral salpingo-oopharectomy, and pelvic lymph node dissection. The final diagnosis of synchronous NIPUC of the bladder and TCC of the ovary was made by histopathology and immunohistochemical studies.
摘要：
卵巢移行细胞癌（TCC）是上皮性卵巢肿瘤的一种罕见亚型，定义为由上皮成分组成的肿瘤，组织学上类似尿路上皮及其肿瘤。原发性尿路癌的卵巢转移很少见。由于组织学相似性，卵巢原发性TCC与转移性膀胱TCC的鉴别诊断具有挑战性。我们介绍了一名49岁的绝经前妇女的病例，该妇女最初被诊断为膀胱非浸润性乳头状尿路上皮癌（NIPUC），并在2年后进行了卵巢同步TCC，同时接受了可疑复发的调查。她接受了根治性膀胱切除术,全子宫切除术,双侧输卵管卵巢切除术，盆腔淋巴结清扫术.通过组织病理学和免疫组织化学研究最终诊断为膀胱的同步NIPUC和卵巢的TCC。
