PDF(Pubmed)
Abstract：
BACKGROUND: The protection of pregnant workers should be based on evidence regarding the risks to reproductive health from exposure to specific work environments and conditions. The objective of this study was to identify the effects on mothers and newborns resulting from environmental exposure to various occupational risks.
METHODS: The study cohort was composed of 399 women admitted to the Obstetrics/Postpartum ward at Hospital La Fe in Valencia, Spain. Face-to-face interviews were conducted to establish associations between workplace exposure during pregnancy and its effects on maternal and newborn health. Sex, anthropometric characteristics, and blood gas analysis in arterial and venous umbilical cord blood at delivery were collected.
RESULTS: A total of 138 women were exposed to biological and/or chemical risks, 122 to physical risks, and 139 at no risk of exposure. In the group with chemical and/or biological risks, the frequency of women who resorted to in vitro fertilization to achieve the studied pregnancy is less than half of the group exposed to physical risks, with statistically significant differences (p = 0.047). The mean values for the arterial analysis in both exposure groups were within average values, with similar pH values between them, but the mean values of PCO2 and PO2 were lower in the group of neonates of mothers exposed to physical risks, with a significant difference for arterial PO2 (p = 0.027).
CONCLUSIONS: Our analysis contributes evidence for planning and prioritizing preventive actions to protect women\'s reproductive health. The results suggest the continuation of a future project that would consider more factors and potentially increase the sample size.
METHODS: The study cohort was composed of 399 women admitted to the Obstetrics/Postpartum ward at Hospital La Fe in Valencia, Spain. Face-to-face interviews were conducted to establish associations between workplace exposure during pregnancy and its effects on maternal and newborn health. Sex, anthropometric characteristics, and blood gas analysis in arterial and venous umbilical cord blood at delivery were collected.
RESULTS: A total of 138 women were exposed to biological and/or chemical risks, 122 to physical risks, and 139 at no risk of exposure. In the group with chemical and/or biological risks, the frequency of women who resorted to in vitro fertilization to achieve the studied pregnancy is less than half of the group exposed to physical risks, with statistically significant differences (p = 0.047). The mean values for the arterial analysis in both exposure groups were within average values, with similar pH values between them, but the mean values of PCO2 and PO2 were lower in the group of neonates of mothers exposed to physical risks, with a significant difference for arterial PO2 (p = 0.027).
CONCLUSIONS: Our analysis contributes evidence for planning and prioritizing preventive actions to protect women\'s reproductive health. The results suggest the continuation of a future project that would consider more factors and potentially increase the sample size.
摘要：
背景：对怀孕工人的保护应基于有关暴露于特定工作环境和条件对生殖健康的风险的证据。这项研究的目的是确定环境暴露于各种职业风险对母亲和新生儿的影响。
方法：研究队列由在瓦伦西亚LaFe医院产科/产后病房住院的399名妇女组成，西班牙。进行了面对面的访谈，以建立怀孕期间工作场所暴露与其对孕产妇和新生儿健康的影响之间的关联。性,人体测量特征,收集分娩时动脉和静脉脐带血的血气分析。
结果：共有138名妇女暴露于生物和/或化学风险，122身体风险，139没有暴露的风险。在具有化学和/或生物风险的组中，采用体外受精来实现研究妊娠的妇女的频率不到暴露于身体风险的组的一半，差异有统计学意义(p=0.047)。两个暴露组的动脉分析平均值均在平均值内，它们之间的pH值相似，但是在暴露于身体风险的母亲的新生儿组中，PCO2和PO2的平均值较低，动脉PO2有显著差异(p=0.027)。
结论：我们的分析为规划和优先考虑保护妇女生殖健康的预防措施提供了证据。结果表明，未来的项目将继续考虑更多因素，并可能增加样本量。
方法：研究队列由在瓦伦西亚LaFe医院产科/产后病房住院的399名妇女组成，西班牙。进行了面对面的访谈，以建立怀孕期间工作场所暴露与其对孕产妇和新生儿健康的影响之间的关联。性,人体测量特征,收集分娩时动脉和静脉脐带血的血气分析。
结果：共有138名妇女暴露于生物和/或化学风险，122身体风险，139没有暴露的风险。在具有化学和/或生物风险的组中，采用体外受精来实现研究妊娠的妇女的频率不到暴露于身体风险的组的一半，差异有统计学意义(p=0.047)。两个暴露组的动脉分析平均值均在平均值内，它们之间的pH值相似，但是在暴露于身体风险的母亲的新生儿组中，PCO2和PO2的平均值较低，动脉PO2有显著差异(p=0.027)。
结论：我们的分析为规划和优先考虑保护妇女生殖健康的预防措施提供了证据。结果表明，未来的项目将继续考虑更多因素，并可能增加样本量。
