Abstract:
The WAMIF study was conducted from 2017 to 2019 to include 314 patients in 30 French investigative centers in France. We have systematically collected the clinical, morphological and biological characteristics of cases of myocardial infarction affecting women under 50 years of age and evaluated their short-term (intra-hospital) and mid-term (at 12 months) prognosis. . The main results were: a particularly high incidence of modifiable risk factors affecting 86% of patients with smoking in the first place in 75% of them. The clinical presentation revealed chest pain in more than 90% of cases. The pathophysiological forms of acute coronary syndrome identified the culprit artery in 90% of cases, MI without obstruction (MINOCA) was found in 17.8% of the ST elevation MI (STEMI), spontaneous dissection in 14.6% of STEMI and 16.3% of NSTEMI. Hospital events included 3 strokes, 3 cases of bleeding and no deaths. At 12 months, follow-up showed no cardiovascular deaths. The results of this study allow us to better understand the particularities of cardiovascular diseases in women and thus to develop targeted strategies for prevention and improvement of their management.
摘要:
WAMIF研究于2017年至2019年进行,包括法国30个法国调查中心的314名患者。我们系统地收集了临床,影响50岁以下妇女的心肌梗死病例的形态学和生物学特征,并评估其短期(医院内)和中期(12个月时)预后。.主要结果是:可改变的危险因素的发生率特别高,影响86%的吸烟患者占75%的首位。临床表现显示超过90%的病例出现胸痛。在90%的病例中,急性冠状动脉综合征的病理生理形式确定了罪犯动脉,无梗阻MI(MINOCA)在17.8%的ST段抬高MI(STEMI)中发现,14.6%的STEMI和16.3%的NSTEMI自发性夹层。医院事件包括3次中风,出血3例,无死亡病例。12个月时,随访显示无心血管死亡.这项研究的结果使我们能够更好地了解女性心血管疾病的特殊性,从而制定有针对性的预防和改善其管理的策略。