UNASSIGNED: The initial literature search was performed in PubMed, the Cochrane Library of Trials, and MEDLINE. The network meta-analysis was performed per the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). Two independent reviewers were assigned data selection and extraction roles. Our study mainly included randomised controlled trials (RCTs) whose titles and abstracts were screened, after which duplicates were excluded. The remaining eligible studies were subjected to full-text analysis to identify data related to the topic of the present study. Analyses were performed using the Cochrane Risk of Bias tool, R software and MS Excel.
UNASSIGNED: Twenty-two studies (involving 9 539 participants) met the inclusion criteria and were subjected to the network meta-analysis. In mortality rates, the greatest rank observed corresponded to a reduction of 71%. The regression of the effects of low caloric intake explained a 5.29% variation in LOS. A weak positive correlation was found between LOS and low caloric intake among critically ill patients in ICUs. Thus, Low caloric intake decreased mortality rates and lowered LOS.
UNASSIGNED: Our study found that low caloric intake reduces mortality rate and hospital LOS among critically ill patients. Secondary outcomes include nosocomial infection, clinical outcomes, functions, digestive infections, improved quality of life, resulting survival rates, ventilator days, bacteremia, blood glucose levels, diarrhoea, and tube replacement. Our findings have clinical implications for clinicians in the ICU, who should consider developing individualised nutritional plans for critically ill patients. Moreover, regular monitoring of nutritional intake and response is crucial. Healthcare providers should closely monitor patients\' nutritional status, vital signs, and clinical outcomes.
■最初的文献检索是在PubMed中进行的,Cochrane试验图书馆,和MEDLINE。根据系统评价和荟萃分析(PRISMA)的首选报告项目进行网络荟萃分析。为两个独立的审阅者分配了数据选择和提取角色。我们的研究主要包括随机对照试验(RCT),其标题和摘要经过筛选,之后排除重复项。其余符合条件的研究进行全文分析,以确定与本研究主题相关的数据。使用Cochrane偏差风险工具进行分析,R软件和MSExcel。
■22项研究(涉及9539名参与者)符合纳入标准,并进行了网络荟萃分析。在死亡率方面,观察到的最高等级对应于71%的减少。低热量摄入影响的回归解释了LOS的5.29%变化。在ICU中的危重患者中,LOS与低热量摄入之间存在弱正相关。因此,低热量摄入降低了死亡率并降低了LOS。
■我们的研究发现,低热量摄入降低了危重患者的死亡率和住院LOS。次要结果包括医院感染,临床结果,功能,消化系统感染,提高生活质量,由此产生的存活率,呼吸机日,菌血症,血糖水平,腹泻,管更换。我们的发现对ICU的临床医生有临床意义,他们应该考虑为危重病人制定个性化的营养计划。此外,定期监测营养摄入和反应至关重要。医疗保健提供者应密切监测患者的营养状况,生命体征,和临床结果。