关键词: Barrett’s esophagus Esophagitis GERD Gastroesophageal reflux Marginal ulcer Mini gastric bypass One-anastomosis gastric bypass Reflux

Mesh : Humans Gastric Bypass / adverse effects Obesity, Morbid / surgery Barrett Esophagus / etiology Gastroesophageal Reflux / etiology complications Esophagitis / etiology complications Gastrectomy / adverse effects Retrospective Studies

来  源:   DOI:10.1007/s11695-023-06866-y

Abstract:
This systematic review and meta-analysis aimed to investigate the incidence of new-onset gastroesophageal reflux, reflux change, esophagitis, Barrett\'s esophagus, and revision due to reflux, gastritis, and marginal ulcer after one-anastomosis gastric bypass (OAGB). We performed subgroup analyses based on primary and revisional OAGB and time of follow-up. Meta-analysis of 87 studies with 27,775 patients showed a 6% rate of new-onset reflux after OAGB. Preoperative reflux status did not change significantly after OAGB. The rate of esophagitis and Barrett\'s esophagus was 15% and 1%, respectively. The new-onset reflux rate after OAGB was significantly higher than gastric bypass but not different with sleeve gastrectomy. The current study showed a relatively low rate of reflux and its complications after OAGB, but it was significantly higher than Roux-en-Y gastric bypass.
摘要:
本系统评价和荟萃分析旨在调查新发胃食管反流的发生率。反流变化,食管炎,巴雷特食管,和由于反流引起的修订,胃炎,一次吻合胃旁路术(OAGB)后的边缘溃疡。我们根据主要和修订的OAGB以及随访时间进行了亚组分析。对87项研究的27,775例患者进行的荟萃分析显示,OAGB后新发反流的发生率为6%。OAGB后,术前返流状态无明显变化。食管炎和Barrett食管的发生率分别为15%和1%,分别。OAGB术后新发反流率显着高于胃旁路术,但与袖状胃切除术没有差异。目前的研究表明,OAGB后的反流率及其并发症相对较低,但明显高于Roux-en-Y胃旁路术.
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