关键词: BBB penetration brain disorder molecular imaging nanobody site-specific labeling

Mesh : Single-Domain Antibodies / metabolism Blood-Brain Barrier / diagnostic imaging metabolism Molecular Imaging / methods

来  源:   DOI:10.1002/jlcr.4069   PDF(Pubmed)

Abstract:
Nanobodies (Nbs) hold significant potential in molecular imaging due to their unique characteristics. However, there are challenges to overcome when it comes to brain imaging. To address these obstacles, collaborative efforts and interdisciplinary research are needed. This article aims to raise awareness and encourage collaboration among researchers from various fields to find solutions for effective brain imaging using Nbs. By fostering cooperation and knowledge sharing, we can make progress in overcoming the existing limitations and pave the way for improved molecular imaging techniques in the future.
摘要:
纳米抗体(Nbs)由于其独特的特性而在分子成像中具有重要的潜力。然而,当涉及到大脑成像时,有一些挑战需要克服。为了解决这些障碍,需要合作努力和跨学科研究。本文旨在提高认识并鼓励来自各个领域的研究人员之间的合作,以找到使用Nbs进行有效脑成像的解决方案。通过促进合作和知识共享,我们可以在克服现有局限性方面取得进展,并为将来改进分子成像技术铺平道路。
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