PDF(Pubmed)
Abstract：
Pilomatrixoma (PMX), also known as calcifying epithelioma of Malherbe, is a rare benign neoplasm that arises from the hair matrix cells, commonly in the head, neck, and upper trunk regions, infrequently affecting upper and lower extremities. It has to two peaks of presentation: under 20 years of age or between 50 and 65 years of age, slightly more common in females. The neoplasm exhibits diverse clinical manifestations and is frequently subject to misdiagnosis with alternative dermatological diseases. We present an atypical case of PMX affecting the upper extremity of a 62-year-old female patient. Surgical removal of the affected tissue under local anesthesia was performed, and subsequent histopathological analysis confirmed the presence of PMX. Based on the literature search we performed, we found out that this pathology is underreported in Jordan, with only one study published describing this tumor in the maxillofacial region. Physicians should be aware of this condition and its different presentations to include it in the differential diagnosis of suspected cases to provide the appropriate management and follow-up.
摘要：
皮房瘤(PMX),也被称为Malherbe钙化上皮瘤，是一种罕见的由毛发基质细胞产生的良性肿瘤，通常在头部，脖子,和上躯干区域，不经常影响上肢和下肢。它有两个表现高峰：20岁以下或50至65岁之间，在女性中更常见。肿瘤表现出多种临床表现，并且经常被其他皮肤病误诊。我们介绍了一例影响62岁女性患者上肢的PMX非典型病例。在局部麻醉下手术切除受影响的组织，随后的组织病理学分析证实了PMX的存在。根据我们进行的文献检索，我们发现这种病理在约旦被低估了，仅发表了一项研究描述了颌面部区域的这种肿瘤。医师应了解这种情况及其不同的表现，以将其纳入疑似病例的鉴别诊断中，以提供适当的管理和随访。
