Abstract：
Research engaging children and adolescents living with HIV (CALWH) is critical for youth-friendly services and HIV care, and researchers need to ensure that such engagement is ethical. We conducted a systematic review to identify key ethical considerations for the engagement of CALWH in research. The review focused on primary research articles conducted in African countries that examined ethical issues in CALWH engaged in research. Ten studies met the inclusion criteria; the following seven key domains were extracted: 1) justifications for engaging CALWH in research; 2) community involvement; 3) informed consent/assent; 4) caregiver involvement; 5) perceptions of benefits; 6) perception of the risks of involvement; and 7) confidentiality. These domains can inform the ethical engagement of CALWH in research.
摘要：
参与儿童和青少年感染艾滋病毒（CALWH）的研究对于青少年友好服务和艾滋病毒护理至关重要，研究人员需要确保这种参与是合乎道德的。我们进行了系统评价，以确定CALWH参与研究的关键伦理考虑因素。该评论的重点是在非洲国家进行的主要研究文章，这些文章研究了从事研究的CALWH的道德问题。十项研究符合纳入标准；提取了以下七个关键领域：1）参与CALWH研究的理由；2）社区参与；3）知情同意/同意；4）护理人员参与；5）对益处的看法；6）对参与风险的看法；7）保密。这些领域可以为CALWH在研究中的伦理参与提供信息。
