Abstract：
UNASSIGNED: The aim is to increase the understanding of lacrimal gland pleomorphic adenoma\'s recurrence rate and the factors that influence it.
UNASSIGNED: A systematic search of PubMed, SCOPUS, Cochrane Library, and CINAHL was conducted following PRISMA guidelines. The data in the included studies were extracted and analyzed.
UNASSIGNED: Twenty-two studies were included representing 963 patients from 12 different countries. The pooled analysis of the recurrence rate was 8.83% (95% CI: 5.08-13.50). In the event of recurrence, there was a 75.17% (95% CI: 65.98-82.94) chance of benign recurrence and a 28.35% (95% CI: 19.66-38.41) chance of malignant recurrences, with malignant recurrence occurring almost exclusively after a benign recurrence. The results showed that 47.09% (95% CI: 24.60 to 70.22) of recurrent tumors had a ruptured pseudocapsule and 6.35% (95% CI: 0.82 to 16.54) had an intact pseudocapsule with a significant difference between the two. Of the recurrent tumors, 51.50% (95% CI: 9.28 to 92.39) were biopsied compared to 8.83% (95% CI: 3.40 to 16.49) of the total; the difference between these two proportions was also found to be significant.
UNASSIGNED: There was a statistically significant difference in the rates of recurrence between tumors that were either biopsied or had a ruptured pseudocapsule compared to those that did not. This evidence adds additional support for excisional biopsy being the procedure of choice for LGPA and reinforces the importance of keeping the pseudocapsule intact during surgical resection.
UNASSIGNED: A systematic search of PubMed, SCOPUS, Cochrane Library, and CINAHL was conducted following PRISMA guidelines. The data in the included studies were extracted and analyzed.
UNASSIGNED: Twenty-two studies were included representing 963 patients from 12 different countries. The pooled analysis of the recurrence rate was 8.83% (95% CI: 5.08-13.50). In the event of recurrence, there was a 75.17% (95% CI: 65.98-82.94) chance of benign recurrence and a 28.35% (95% CI: 19.66-38.41) chance of malignant recurrences, with malignant recurrence occurring almost exclusively after a benign recurrence. The results showed that 47.09% (95% CI: 24.60 to 70.22) of recurrent tumors had a ruptured pseudocapsule and 6.35% (95% CI: 0.82 to 16.54) had an intact pseudocapsule with a significant difference between the two. Of the recurrent tumors, 51.50% (95% CI: 9.28 to 92.39) were biopsied compared to 8.83% (95% CI: 3.40 to 16.49) of the total; the difference between these two proportions was also found to be significant.
UNASSIGNED: There was a statistically significant difference in the rates of recurrence between tumors that were either biopsied or had a ruptured pseudocapsule compared to those that did not. This evidence adds additional support for excisional biopsy being the procedure of choice for LGPA and reinforces the importance of keeping the pseudocapsule intact during surgical resection.
摘要：
■目的是提高对泪腺多形性腺瘤的复发率及其影响因素的认识。
■对PubMed的系统搜索，Scopus,科克伦图书馆,和CINAHL按照PRISMA指南进行。对纳入研究的数据进行提取和分析。
■包括22项研究，来自12个不同国家的963名患者。合并分析的复发率为8.83%(95%CI:5.08-13.50)。如果复发，良性复发的概率为75.17%(95%CI:65.98-82.94),恶性复发的概率为28.35%(95%CI:19.66-38.41),恶性复发几乎完全发生在良性复发之后。结果显示，47.09%(95%CI:24.60～70.22)的复发性肿瘤有假包膜破裂，6.35%(95%CI:0.82～16.54)的肿瘤有完整的假包膜，两者之间有显著差异。在复发性肿瘤中，51.50％（95％CI：9.28至92.39）进行了活检，而总数为8.83％（95％CI：3.40至16.49）；这两个比例之间的差异也被发现是显着的。
活检或有假包膜破裂的肿瘤与未活检的肿瘤相比，复发率有统计学上的显着差异。该证据为LGPA的首选手术切除活检提供了额外的支持，并加强了在手术切除期间保持假包膜完整的重要性。
■对PubMed的系统搜索，Scopus,科克伦图书馆,和CINAHL按照PRISMA指南进行。对纳入研究的数据进行提取和分析。
■包括22项研究，来自12个不同国家的963名患者。合并分析的复发率为8.83%(95%CI:5.08-13.50)。如果复发，良性复发的概率为75.17%(95%CI:65.98-82.94),恶性复发的概率为28.35%(95%CI:19.66-38.41),恶性复发几乎完全发生在良性复发之后。结果显示，47.09%(95%CI:24.60～70.22)的复发性肿瘤有假包膜破裂，6.35%(95%CI:0.82～16.54)的肿瘤有完整的假包膜，两者之间有显著差异。在复发性肿瘤中，51.50％（95％CI：9.28至92.39）进行了活检，而总数为8.83％（95％CI：3.40至16.49）；这两个比例之间的差异也被发现是显着的。
活检或有假包膜破裂的肿瘤与未活检的肿瘤相比，复发率有统计学上的显着差异。该证据为LGPA的首选手术切除活检提供了额外的支持，并加强了在手术切除期间保持假包膜完整的重要性。
