Abstract：
OBJECTIVE: The objective of this scoping review is to understand the extent, type of evidence, and overall findings in relation to the impact of endoscopic treatment (ET) on health-related quality of life (HR-QoL) in patients with Barrett\'s dysplasia and early oesophageal cancer.
METHODS: A comprehensive search was conducted for literature between 2001 and 2022 in computerised databases (PubMed, Embase, Cochrane Library, and CINAHL Complete). Additionally, sources of unpublished literature were searched in Google Advanced Search. After title and abstract checking, full-text papers were retrieved. Data were extracted, synthesised, key information tabulated, and a narrative synthesis completed.
RESULTS: Six studies were included in the final analysis. Twelve different survey tools were utilised across all studies. Study designs included three randomised controlled studies, two prospective observational studies, and a single retrospective observational study. The average age of study participants ranged from 60.3 to 71.0 years. Two studies evaluated HR-QoL as primary outcome measures, but most research evaluated HR-QoL as a secondary outcome. Health domains evaluated in the studies focussed on the biophysical and psychosocial aspects of quality of life.
CONCLUSIONS: A small number of research studies have been conducted in this area. Due to the heterogeneity and small number of included studies, it was difficult to draw conclusions about the impact of specific ET types on HR-QoL. Overall, there were perceived psychological benefits while undergoing ET. Future research could target specific ET subtypes and measure HR-QoL at baseline and post-procedures in the short and long term.
METHODS: A comprehensive search was conducted for literature between 2001 and 2022 in computerised databases (PubMed, Embase, Cochrane Library, and CINAHL Complete). Additionally, sources of unpublished literature were searched in Google Advanced Search. After title and abstract checking, full-text papers were retrieved. Data were extracted, synthesised, key information tabulated, and a narrative synthesis completed.
RESULTS: Six studies were included in the final analysis. Twelve different survey tools were utilised across all studies. Study designs included three randomised controlled studies, two prospective observational studies, and a single retrospective observational study. The average age of study participants ranged from 60.3 to 71.0 years. Two studies evaluated HR-QoL as primary outcome measures, but most research evaluated HR-QoL as a secondary outcome. Health domains evaluated in the studies focussed on the biophysical and psychosocial aspects of quality of life.
CONCLUSIONS: A small number of research studies have been conducted in this area. Due to the heterogeneity and small number of included studies, it was difficult to draw conclusions about the impact of specific ET types on HR-QoL. Overall, there were perceived psychological benefits while undergoing ET. Future research could target specific ET subtypes and measure HR-QoL at baseline and post-procedures in the short and long term.
摘要：
目的：本范围审查的目的是了解范围，证据类型,以及与内镜治疗（ET）对Barrett发育不良和早期食管癌患者健康相关生活质量（HR-QoL）的影响相关的总体发现。
方法：对2001年至2022年之间在计算机数据库中的文献进行了全面搜索(PubMed，Embase,科克伦图书馆,和CINAHL完成）。此外,在Google高级搜索中搜索了未发表文献的来源。在标题和摘要检查之后，检索了全文论文。数据被提取，合成，关键信息列表，并完成了叙事综合。
结果：六项研究纳入最终分析。在所有研究中使用了12种不同的调查工具。研究设计包括三项随机对照研究，两项前瞻性观察性研究，和一项回顾性观察研究。研究参与者的平均年龄为60.3至71.0岁。两项研究评估了HR-QoL作为主要结果指标，但大多数研究将HR-QoL评估为次要结局。研究中评估的健康领域侧重于生活质量的生物物理和心理社会方面。
结论：在这一领域已经进行了少量的研究。由于异质性和纳入研究数量少，很难得出关于特定ET类型对HR-QoL的影响的结论。总的来说,在接受ET时，有明显的心理益处。未来的研究可以针对特定的ET亚型，并在基线和术后短期和长期测量HR-QoL。
方法：对2001年至2022年之间在计算机数据库中的文献进行了全面搜索(PubMed，Embase,科克伦图书馆,和CINAHL完成）。此外,在Google高级搜索中搜索了未发表文献的来源。在标题和摘要检查之后，检索了全文论文。数据被提取，合成，关键信息列表，并完成了叙事综合。
结果：六项研究纳入最终分析。在所有研究中使用了12种不同的调查工具。研究设计包括三项随机对照研究，两项前瞻性观察性研究，和一项回顾性观察研究。研究参与者的平均年龄为60.3至71.0岁。两项研究评估了HR-QoL作为主要结果指标，但大多数研究将HR-QoL评估为次要结局。研究中评估的健康领域侧重于生活质量的生物物理和心理社会方面。
结论：在这一领域已经进行了少量的研究。由于异质性和纳入研究数量少，很难得出关于特定ET类型对HR-QoL的影响的结论。总的来说,在接受ET时，有明显的心理益处。未来的研究可以针对特定的ET亚型，并在基线和术后短期和长期测量HR-QoL。
