PDF(Pubmed)
Abstract：
Pituitary macroadenoma and angiofibroma are two distinct and diverse types of tumors that can develop in different anatomical locations and clinical characteristics and are not typically related to each other in terms of their hormonal or developmental aspects. This case describes an adult male with pituitary macroadenoma with nasal angiofibroma. A 35-year-old male was diagnosed with pituitary macroadenoma and incidentally found to have juvenile nasopharyngeal angiofibroma (NPA). The patient underwent a diagnostic workup, including imaging studies and hormonal assays, which confirmed the concomitant presence of both tumors. The patient underwent successful endoscopic surgical excision of the NPA and transnasal transsphenoidal endoscopic pituitary macroadenoma excision as a two-stage operation. The patient was followed up postoperatively and had no evidence of tumor recurrence or hormonal imbalances. The importance of complete and comprehensive diagnostic workup and multidisciplinary management in achieving successful and optimum treatment outcomes for coexisting NPA and pituitary macroadenoma in an adult patient is highlighted in the present report.
摘要：
垂体大腺瘤和血管纤维瘤是两种不同类型的肿瘤，可以在不同的解剖位置和临床特征中发展，并且在激素或发育方面通常彼此不相关。该病例描述了一名患有垂体大腺瘤伴鼻血管纤维瘤的成年男性。一名35岁的男性被诊断出患有垂体大腺瘤，并偶然发现患有青少年鼻咽血管纤维瘤（NPA）。病人接受了诊断检查,包括成像研究和激素检测，这证实了两种肿瘤的同时存在。该患者成功进行了NPA的内镜手术切除和经鼻蝶入路内镜下垂体大腺瘤切除术，分为两阶段。患者术后随访，没有肿瘤复发或激素失衡的证据。本报告强调了完整和全面的诊断检查和多学科管理对于实现成人患者共存的NPA和垂体大腺瘤的成功和最佳治疗结果的重要性。
