PDF(Pubmed)
Abstract：
Sexual selection is the differential reproductive success of individuals, resulting from competition for mates, mate choice, or success in fertilization. In primates, this selective pressure often leads to the development of exaggerated traits which play a role in sexual competition and successful reproduction. In order to gain insight into the mechanisms driving the development of sexually selected traits, we used an unbiased genome-wide approach across 21 primate species to correlate individual rates of protein evolution to relative testes size and sexual dimorphism in body size, 2 anatomical hallmarks of sexual selection in mammals. Among species with presumed high levels of sperm competition, we detected strong conservation of testes-specific proteins responsible for spermatogenesis and ciliary form and function. In contrast, we identified accelerated evolution of female reproductive proteins expressed in the vagina, cervix, and fallopian tubes in these same species. Additionally, we found accelerated protein evolution in lymphoid tissue, indicating that adaptive immune functions may also be influenced by sexual selection. This study demonstrates the distinct complexity of sexual selection in primates revealing contrasting patterns of protein evolution between male and female reproductive tissues.
摘要：
性选择是个体不同的生殖成功，由于配偶的竞争，择偶,或受精成功。在灵长类动物中，这种选择性压力通常会导致夸张特征的发展，这些特征在性竞争和成功繁殖中起作用。为了深入了解推动性选择特征发展的机制，我们在21个灵长类物种中使用了一种无偏见的全基因组方法，将蛋白质进化的个体速率与相对睾丸大小和身体大小的性二态性相关联，哺乳动物性选择的两个解剖学标志。在推测精子竞争水平高的物种中，我们检测到负责精子发生和纤毛形式和功能的睾丸特异性蛋白质的强保守性。相比之下,我们发现了在阴道中表达的女性生殖蛋白的加速进化，子宫颈,和输卵管在这些物种中。此外,我们在淋巴组织中发现了加速的蛋白质进化,这表明适应性免疫功能也可能受到性选择的影响。这项研究证明了灵长类动物性选择的独特复杂性，揭示了男性和女性生殖组织之间蛋白质进化的对比模式。
