成纤维细胞激活蛋白通过蛋白酶非依赖性作用促进肿瘤转移稳定。
关键词: CP: Cancer MT1- MMP TWIST1 breast cancer extracellular matrix fibroblast activation protein invadopodia invasion matrix degradation tumor metastasis
Mesh : Humans Female Podosomes / metabolism Cell Line, Tumor Peptide Hydrolases / metabolism Neoplasm Invasiveness / pathology Breast Neoplasms / pathology Membrane Proteins / metabolism Serine Endopeptidases / metabolism Fibroblasts / metabolism Extracellular Matrix / metabolism Melanoma, Cutaneous Malignant
来 源:
DOI:10.1016/j.celrep.2023.113302
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