PDF(Pubmed)
Abstract：
Background: Utilizing the bioactive compounds found in pigmented rice might significantly reduce the risk of breast cancer. This study aims to systematically review existing literature on the benefit of Asian pigmented rice bioactive compounds and their implication in breast cancer. Methods: Searches of the literature were conducted in two databases (Scopus and PubMed) for a systematic review. The keywords resulted in a total of 407 articles, consisting of 103 PubMed and 304 Scopus articles. 32 manuscripts were excluded because the article was over 10 years old. After excluding book chapters and non-English languages, we had 278 potential articles to be reviewed. After checking and screening the title and abstract and eliminating duplicate articles, then 66 articles were obtained. After the selection and elimination of the full-text manuscripts, finally 10 of them which met the inclusion criteria. Result: The included studies in this review were entirely based in Asia. The year of publication ranged from 2013 to 2020. Half of included studies used black rice extract, two used red jasmine rice extracts, and three used Korean rice extracts (black, red, dark purple and brown rice). All studies were conducted in vitro and three studies were compared with in vivo tests on female mice. The pigmented rice is mainly black, red, and dark purple rice, and contains a variety of peonidin-3-glucoside, cyanidin-3-glucoside, γ-oryzanol, γ-tocotrienol, proanthocyanidin, cinnamic acid, and anthocyanins that may act as pro-apoptotic, anti-proliferative, and anti-metastasis of the breast cancer cells. Conclusion: Pigmented rice is a beneficial food which possessed bioactive compounds that may have significant potential concerning a breast cancer.
摘要：
背景：利用色素大米中发现的生物活性化合物可以显着降低患乳腺癌的风险。本研究旨在系统回顾有关亚洲色素水稻生物活性化合物的益处及其在乳腺癌中的意义的现有文献。方法：在两个数据库（Scopus和PubMed）中进行文献搜索，以进行系统评价。这些关键词总共产生了407篇文章，由103篇PubMed和304篇Scopus文章组成。32份手稿被排除在外，因为这篇文章已经超过10年了。在排除书籍章节和非英语语言之后，我们有278篇可能的文章需要审查.在检查和筛选标题和摘要并消除重复文章之后，然后获得66篇文章。在全文手稿的选择和淘汰之后，最后10个符合纳入标准。结果：本综述中纳入的研究完全基于亚洲。出版年份从2013年到2020年不等。纳入研究的一半使用黑米提取物，两种用过的红茉莉米提取物，和三种使用的韩国大米提取物（黑色，红色,深紫色和糙米）。所有研究均在体外进行，三项研究与雌性小鼠的体内试验进行了比较。色素大米主要是黑色的，红色,和深紫色的米饭，含有多种牡丹苷-3-葡萄糖苷，花青素-3-葡萄糖苷，γ-谷维素，γ-生育三烯酚，原花青素，肉桂酸,花青素可能起到促凋亡的作用，抗增殖，和抗乳腺癌细胞的转移。结论：色素大米是一种有益的食物，具有生物活性化合物，可能具有与乳腺癌有关的显着潜力。
