PDF(Pubmed)
Abstract：
UNASSIGNED: The coil handle orientation plays a pivotal role in the therapeutic efficacy of repetitive transcranial magnetic stimulation (rTMS). However, there is currently no consensus on the optimal individualized coil handle orientation, especially for non-motor areas.
UNASSIGNED: The present case reported a short-term effect of functional connectivity (FC)-guided rTMS with coil handle posterior-anterior 45° (PA45°) and posterior-anterior 135° (PA135°) on a patient with insomnia. Notably, in this case, the PA45° orientation was nearly perpendicular to the adjacent sulcus, while the PA135° orientation was almost parallel to it. Local brain activity and functional connectivity were assessed using resting-state functional magnetic resonance imaging (RS-fMRI). Additionally, motor evoked potentials (MEPs) were captured both pre and post-rTMS sessions.
UNASSIGNED: The coil handle orientation PA45° outperformed the PA135° in both RS-fMRI and MEP outcomes. Moreover, a 9-day rTMS treatment led to discernible improvements in symptoms of depression and anxiety, complemented by a modest enhancement in sleep quality.
UNASSIGNED: The present case reported a short-term effect of functional connectivity (FC)-guided rTMS with coil handle posterior-anterior 45° (PA45°) and posterior-anterior 135° (PA135°) on a patient with insomnia. Notably, in this case, the PA45° orientation was nearly perpendicular to the adjacent sulcus, while the PA135° orientation was almost parallel to it. Local brain activity and functional connectivity were assessed using resting-state functional magnetic resonance imaging (RS-fMRI). Additionally, motor evoked potentials (MEPs) were captured both pre and post-rTMS sessions.
UNASSIGNED: The coil handle orientation PA45° outperformed the PA135° in both RS-fMRI and MEP outcomes. Moreover, a 9-day rTMS treatment led to discernible improvements in symptoms of depression and anxiety, complemented by a modest enhancement in sleep quality.
摘要：
■线圈手柄方向在重复经颅磁刺激（rTMS）的治疗功效中起着关键作用。然而,目前还没有关于最佳个性化线圈手柄方向的共识，特别是对于非运动区域。
■本病例报道了功能性连接（FC）引导的rTMS带线圈手柄前后45°（PA45°）和前后135°（PA135°）对失眠患者的短期影响。值得注意的是,在这种情况下,PA45°方向几乎垂直于相邻的沟，而PA135°取向几乎与它平行。使用静息状态功能磁共振成像（RS-fMRI）评估局部脑活动和功能连通性。此外,在rTMS会话之前和之后都捕获了运动诱发电位（MEP）。
■在RS-fMRI和MEP结果中，线圈手柄方向PA45°优于PA135°。此外，9天的rTMS治疗导致抑郁症和焦虑症的明显改善，辅之以睡眠质量的适度提高。
■本病例报道了功能性连接（FC）引导的rTMS带线圈手柄前后45°（PA45°）和前后135°（PA135°）对失眠患者的短期影响。值得注意的是,在这种情况下,PA45°方向几乎垂直于相邻的沟，而PA135°取向几乎与它平行。使用静息状态功能磁共振成像（RS-fMRI）评估局部脑活动和功能连通性。此外,在rTMS会话之前和之后都捕获了运动诱发电位（MEP）。
■在RS-fMRI和MEP结果中，线圈手柄方向PA45°优于PA135°。此外，9天的rTMS治疗导致抑郁症和焦虑症的明显改善，辅之以睡眠质量的适度提高。
