PDF(Pubmed)
Abstract：
This review mainly highlights our studies on the synthesis of one-handed helical polymers with a static memory of helicity based on the noncovalent helicity induction with a helical-sense bias and subsequent memory of the helicity approach that we developed during the past decade. Apart from the previous approaches, an excess one-handed helical conformation, once induced by nonracemic molecules, is immediately retained (\"memorized\") after the complete removal of the nonracemic molecules, accompanied by a significant amplification of the asymmetry, providing novel switchable chiral materials for chromatographic enantioseparation and asymmetric catalysis as well as a highly sensitive colorimetric and fluorescence chiral sensor. A conceptually new one-handed helix formation in a racemic helical polymer composed of racemic repeating units through the deracemization of the pendants is described.
摘要：
这篇综述主要重点介绍了我们对单手螺旋聚合物的合成研究，该聚合物具有基于非共价螺旋感应的静态螺旋记忆，并具有螺旋感应偏差和我们在过去十年中开发的螺旋方法的后续记忆。除了以前的方法，多余的单手螺旋构象，一旦被非外消旋分子诱导，在完全去除非外消旋分子后立即保留（“记忆”），伴随着不对称性的显著放大，提供用于色谱对映分离和不对称催化的新型可转换手性材料以及高灵敏度的比色和荧光手性传感器。描述了一种概念上新的单手螺旋形成的外消旋螺旋聚合物，该聚合物由外消旋重复单元组成，通过吊坠的去壳化。
