Abstract：
The purpose of this study was to determine the relationship between vertebral margins at individual vertebral levels between T12-L5 vertebra and chronological age and develop predictive models. Three hundred and nineteen CT scans from a medical imaging database in North America were randomly selected. Three superior and inferior vertebral margin sites were scored based on observable age-related changes. All individual vertebral margin site scores significantly correlated with age at death with Pearson r values ranging from 0.47 to 0.77. Totaling the individual vertebral margin site scores for L1-L5 improved Pearson r to 0.92. All resulting predictive models were significant, and the best models predicted age at death within 10 years 70%-76% of the time for males, females, and combined male and females. In conclusion, this study produced accurate and reliable models to predict age at death using age-related changes in the spine for a North American population.
摘要：
这项研究的目的是确定T12-L5椎骨与实际年龄之间各个椎骨水平的椎骨边缘之间的关系，并开发预测模型。从北美的医学成像数据库中随机选择了三百十九次CT扫描。根据可观察到的与年龄相关的变化对三个上和下椎骨边缘部位进行评分。所有单个椎骨边缘部位得分与死亡年龄显着相关，Pearsonr值范围为0.47至0.77。L1-L5的单个椎骨边缘部位评分总计将Pearsonr提高到0.92。所有得到的预测模型都是显著的，最好的模型预测了10年内男性死亡年龄的70%-76%，女性,结合了男性和女性。总之,这项研究利用北美人群与年龄相关的脊柱变化,建立了准确可靠的模型来预测死亡年龄.
