PDF(Pubmed)
Abstract：
Elizabethkingia anophelis, a gram-negative bacillus belonging to the Flavobacteriaceae family, is found in various environmental sources and has been associated with community and hospital outbreaks. Correct identification is crucial, guided by advanced genomic techniques, i.e., matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) system with an updated database. The case fatality rate, ranging from 24 to 60%, underscores the need for timely recognition and appropriate management. Additionally, Elizabethkingia presents a challenge due to its recent discovery, misidentification history, and drug resistance. Here, we present a case of fatal infection in a 30-year-old male, who presented with pneumonia. It gradually progressed and ultimately proved fatal underscoring the virulence of the pathogen involved. It was a diagnostic challenge as it likely is the first reported instance of Elizabethkingia anophelis infection from Nepal.
摘要：
伊丽莎白金根按蚊,属于黄杆菌科的革兰氏阴性杆菌，在各种环境来源中发现，并与社区和医院的疫情有关。正确的识别是至关重要的,在先进的基因组技术的指导下，即，具有更新数据库的矩阵辅助激光解吸电离飞行时间质谱（MALDI-TOFMS）系统。病死率，从24%到60%不等，强调需要及时承认和适当的管理。此外,Elizabethkingia提出了一个挑战，由于它最近的发现，错误识别历史，和抗药性。这里,我们介绍了一例30岁男性的致命感染病例,患有肺炎的人。它逐渐发展并最终证明是致命的，突显了所涉及病原体的毒力。这是一个诊断挑战，因为它可能是尼泊尔首次报道的伊丽莎白金根按蚊感染实例。
