Abstract：
Accurate detection and monitoring of therapeutic drug levels are vital for effective patient care and treatment management. Aptamers, composed of single-stranded DNA or RNA molecules, are integral components of biosensors designed for both qualitative and quantitative detection of biological samples. Aptasensors play crucial roles in target identification, validation, detection of drug-target interactions and screening potential of drug candidates. This review focuses on the pivotal role of aptasensors in early disease detection, particularly in identifying biomarkers associated with various diseases such as cancer, infectious diseases and cardiovascular disorders. Aptasensors have demonstrated exceptional potential in enhancing disease diagnostics and monitoring therapeutic drug levels. Aptamer-based biosensors represent a transformative technology in the field of healthcare, enabling precise diagnostics, drug monitoring and disease detection.
摘要：
准确检测和监测治疗药物水平对于有效的患者护理和治疗管理至关重要。适体,由单链DNA或RNA分子组成，是为生物样品的定性和定量检测而设计的生物传感器的组成部分。Aptasensor在目标识别中起着至关重要的作用，验证,检测药物-靶标相互作用和筛选候选药物的潜力。这篇综述的重点是aptasensor在早期疾病检测中的关键作用，特别是在识别与癌症等各种疾病相关的生物标志物方面，传染病和心血管疾病。Aptasensor在增强疾病诊断和监测治疗药物水平方面表现出非凡的潜力。基于适体的生物传感器代表了医疗保健领域的变革性技术，实现精确诊断，药物监测和疾病检测。
