Abstract:
Carbohydrate antigen (CA 19-9) is the most validated marker for both sensitivity and specificity of pancreatic adenocarcinoma used to aid diagnosis of symptomatic patients as well as to evaluate the progression or treatment of disease. Though higher levels of CA 19-9 tend to correlate with neoplastic disease, elevated levels are also often seen in patients with benign gastrointestinal diseases, such as obstructive jaundice and pancreatitis. We present a case of a 74-year-old male who was admitted for abdominal pain and worsening jaundice who was diagnosed with extensive pancreatic necrosis and an underlying invasive pancreatic adenocarcinoma whose serum level of CA 19-9 was found to be extraordinarily high.
摘要:
碳水化合物抗原(CA19-9)是胰腺腺癌敏感性和特异性最有效的标志物,用于帮助诊断有症状的患者以及评估疾病的进展或治疗。虽然较高水平的CA19-9倾向于与肿瘤疾病相关,升高的水平也常见于良性胃肠道疾病患者,如阻塞性黄疸和胰腺炎。我们介绍了一例74岁的男性,因腹痛和黄疸恶化而入院,被诊断为广泛的胰腺坏死和潜在的浸润性胰腺腺癌,其血清CA19-9水平异常高。