关键词: antibiotic therapy cervical cerclage cervical culture cervical insufficiency microbiome neonatal outcome

Mesh : Pregnancy Infant, Newborn Humans Female Child Cerclage, Cervical / adverse effects methods Cervix Uteri / surgery Premature Birth / epidemiology Uterine Cervical Incompetence / surgery etiology Pregnancy Outcome Retrospective Studies

来  源:   DOI:10.5603/gpl.96507

Abstract:
OBJECTIVE: The perioperative management of the cervical cerclage procedure is not unified. In general population controlling microbiome cervical status does not affect obstetric outcomes, but it might be beneficial in patients with cervical insufficiency. The aim of our study was to present the obstetric, neonatal and pediatric outcomes of patients undergoing the cervical cerclage placement procedure in our obstetric department using a regimen of care that includes control of the microbiological status of the cervix and elimination of the pathogens detected.
METHODS: Thirty-five patients undergoing cervical cerclage in the 2nd Department of Obstetrics and Gynecology, Medical University of Warsaw, were included in the study. The procedure was performed only after receiving a negative culture from the cervical canal.
RESULTS: Thirty-one (88.6%) patients delivered after the 34th and twenty-eight (80.0%) after the 37th week of gestation. The colonization of the genital tract was present in 31% of patients prior to the procedure, in 42% of patients - during the subsequent pregnancy course and in 48% of patients - before delivery. A total of 85% of patients who had miscarriage or delivered prematurely had abnormal cervical cultures. In patients with normal cervical cultures, and 91.7% of women delivered at term. No abnormalities in children\'s development were found.
CONCLUSIONS: Controlling microbiological status of the cervical canal results in better or similar outcomes to those reported by other authors in terms of obstetric and neonatal outcomes. Active eradication of the reproductive tract colonization potentially increases the effectiveness of the cervical cerclage placement.
摘要:
目的:宫颈环扎术的围手术期处理不统一。在一般人群中,控制微生物组宫颈状态并不影响产科结局,但它可能对宫颈机能不全患者有益。我们研究的目的是介绍产科,在我们的产科使用包括控制宫颈微生物学状态和消除检测到的病原体的护理方案进行宫颈环扎术的患者的新生儿和儿科结局。
方法:妇产科二科35例宫颈环扎术患者,华沙医科大学,包括在研究中。仅在从宫颈管接受阴性培养后进行该程序。
结果:31例(88.6%)患者在妊娠34周后分娩,28例(80.0%)患者在妊娠37周后分娩。31%的患者在手术前存在生殖道定植,42%的患者-在随后的怀孕过程中和48%的患者-分娩前。共有85%的流产或过早分娩的患者宫颈培养异常。在宫颈培养正常的患者中,91.7%的女性在足月分娩。未发现儿童发育异常。
结论:与其他作者报道的产科和新生儿结局相比,控制宫颈管的微生物学状态可带来更好或相似的结局。积极根除生殖道定植可能会增加宫颈环扎术放置的有效性。
公众号