Abstract：
OBJECTIVE: This cross-sectional study aimed to observe the occurrence of metabolic syndrome in untreated individuals with bipolar disorders.
METHODS: A total of 125 untreated individuals with bipolar disorders were collected as the study group, and 201 cases from the health examination centre of our hospital were selected as the control group. The participants enrolled were assessed for general demographic data, case characteristics, and metabolic indexes including body mass index (BMI), blood pressure, triglyceride, high-density lipoprotein-cholesterol, cholesterol, low-density lipoprotein-cholesterol, and fasting plasma glucose.
RESULTS: The incidence of metabolic syndrome in the bipolar disorders group was higher compared to the control group (9.6% VS. 8.5%). After calibrating sex and age data, a significant difference between the two groups was observed (P < 0.05). Diastolic and systolic blood pressure were higher in the bipolar disorders group compared to the control group (P < 0.01). Men with bipolar disorders had a higher risk of developing metabolic syndrome than women (14.5% vs. 5.8%). Bipolar disorders, sex, age, and BMI were identified as independent risk factors for metabolic syndrome. No significant difference was found in terms of metabolic index and incidence of metabolic syndrome between individuals with depressive episodes (n = 37) and manic episodes (n = 75).
CONCLUSIONS: Patients with bipolar disorders were found to have a higher risk of developing metabolic syndrome than healthy individuals. Bipolar disorders, male sex, age, and BMI may contribute to an increased risk of developing metabolic syndrome.
METHODS: A total of 125 untreated individuals with bipolar disorders were collected as the study group, and 201 cases from the health examination centre of our hospital were selected as the control group. The participants enrolled were assessed for general demographic data, case characteristics, and metabolic indexes including body mass index (BMI), blood pressure, triglyceride, high-density lipoprotein-cholesterol, cholesterol, low-density lipoprotein-cholesterol, and fasting plasma glucose.
RESULTS: The incidence of metabolic syndrome in the bipolar disorders group was higher compared to the control group (9.6% VS. 8.5%). After calibrating sex and age data, a significant difference between the two groups was observed (P < 0.05). Diastolic and systolic blood pressure were higher in the bipolar disorders group compared to the control group (P < 0.01). Men with bipolar disorders had a higher risk of developing metabolic syndrome than women (14.5% vs. 5.8%). Bipolar disorders, sex, age, and BMI were identified as independent risk factors for metabolic syndrome. No significant difference was found in terms of metabolic index and incidence of metabolic syndrome between individuals with depressive episodes (n = 37) and manic episodes (n = 75).
CONCLUSIONS: Patients with bipolar disorders were found to have a higher risk of developing metabolic syndrome than healthy individuals. Bipolar disorders, male sex, age, and BMI may contribute to an increased risk of developing metabolic syndrome.
摘要：
目的：这项横断面研究旨在观察未经治疗的双相情感障碍患者代谢综合征的发生。
方法：收集125名未经治疗的双相情感障碍患者作为研究组，选取我院健康体检中心201例作为对照组。对登记的参与者进行了一般人口统计数据评估，案例特征,和代谢指标，包括体重指数(BMI)，血压,甘油三酯，HDL-C,胆固醇,LDL-C,和空腹血糖。
结果：与对照组相比，双相情感障碍组的代谢综合征发生率更高（9.6％VS。8.5%）。在校准性别和年龄数据后，两组比较差异有统计学意义(P<0.05)。双相障碍组舒张压和收缩压高于对照组(P<0.01)。患有双相情感障碍的男性患代谢综合征的风险高于女性（14.5％vs.5.8%）。双相情感障碍,性别,年龄,和BMI被确定为代谢综合征的独立危险因素。在抑郁发作（n=37）和躁狂发作（n=75）的个体之间，代谢指数和代谢综合征的发生率没有显着差异。
结论：双相情感障碍患者患代谢综合征的风险高于健康个体。双相情感障碍,男性,年龄,和BMI可能导致发生代谢综合征的风险增加。
方法：收集125名未经治疗的双相情感障碍患者作为研究组，选取我院健康体检中心201例作为对照组。对登记的参与者进行了一般人口统计数据评估，案例特征,和代谢指标，包括体重指数(BMI)，血压,甘油三酯，HDL-C,胆固醇,LDL-C,和空腹血糖。
结果：与对照组相比，双相情感障碍组的代谢综合征发生率更高（9.6％VS。8.5%）。在校准性别和年龄数据后，两组比较差异有统计学意义(P<0.05)。双相障碍组舒张压和收缩压高于对照组(P<0.01)。患有双相情感障碍的男性患代谢综合征的风险高于女性（14.5％vs.5.8%）。双相情感障碍,性别,年龄,和BMI被确定为代谢综合征的独立危险因素。在抑郁发作（n=37）和躁狂发作（n=75）的个体之间，代谢指数和代谢综合征的发生率没有显着差异。
结论：双相情感障碍患者患代谢综合征的风险高于健康个体。双相情感障碍,男性,年龄,和BMI可能导致发生代谢综合征的风险增加。
