PDF(Pubmed)
Abstract：
Ulcerative colitis (UC) is a subtype of inflammatory bowel disease that results in inflammation and ulceration in the lining of the large intestine. Patients with UC are frequently prescribed immunosuppressive medications to treat their symptoms, resulting in an increased risk of reactivation of many latent viruses, including herpes simplex virus (HSV) and cytomegalovirus (CMV). However, it is rare for a patient to present with simultaneous reactivation of both viruses. Here, we document the presentation, hospital course, and clinical findings of a UC patient with HSV and CMV dual infection. We also describe treatment strategies and prophylactic measures for managing a dual infection. This is seen through initiating valganciclovir in the outpatient setting following the diagnosis.
摘要：
溃疡性结肠炎（UC）是炎症性肠病的一种亚型，可导致大肠衬里的炎症和溃疡。UC患者经常服用免疫抑制药物来治疗他们的症状，导致许多潜伏病毒重新激活的风险增加，包括单纯疱疹病毒（HSV）和巨细胞病毒（CMV）。然而,患者很少同时出现两种病毒的再激活。这里,我们记录演示文稿，医院课程,1例HSV和CMV双重感染的UC患者的临床表现。我们还描述了管理双重感染的治疗策略和预防措施。这可以通过在诊断后的门诊环境中开始使用伐更昔洛韦来观察。
