Abstract:
Non-communicable diseases (NCDs) represent the leading cause of mortality and disability worldwide. Robust evidence has demonstrated that modifiable lifestyle factors such as unhealthy diet, smoking, alcohol consumption and physical inactivity are the primary causes of NCDs. Although a series of guidelines for the management of NCDs have been published in China, these guidelines mainly focus on clinical practice targeting clinicians rather than the general population, and the evidence for NCD prevention based on modifiable lifestyle factors has been disorganized. Therefore, comprehensive and evidence-based guidance for the risk management of major NCDs for the general Chinese population is urgently needed. To achieve this overarching aim, we plan to develop a series of expert consensuses covering 15 major NCDs on health risk management for the general Chinese population. The objectives of these consensuses are (1) to identify and recommend suitable risk assessment methods for the Chinese population; and (2) to make recommendations for the prevention of major NCDs by integrating the current best evidence and experts\' opinions.
For each expert consensus, we will establish a consensus working group comprising 40-50 members. Consensus questions will be formulated by integrating literature reviews, expert opinions, and an online survey. Systematic reviews will be considered as the primary evidence sources. We will conduct new systematic reviews if there are no eligible systematic reviews, the methodological quality is low, or the existing systematic reviews have been published for more than 3 years. We will evaluate the quality of evidence and make recommendations according to the GRADE approach. The consensuses will be reported according to the Reporting Items for Practice Guidelines in Healthcare (RIGHT).
摘要:
非传染性疾病(NCDs)是全球死亡和残疾的主要原因。强有力的证据表明,可改变的生活方式因素,如不健康的饮食,吸烟,饮酒和缺乏身体活动是非传染性疾病的主要原因。尽管中国已经发布了一系列非传染性疾病管理指南,这些指南主要侧重于针对临床医生的临床实践,而不是一般人群,基于可改变的生活方式因素的非传染性疾病预防证据已经混乱。因此,迫切需要为中国普通人群提供全面和循证的非传染性疾病风险管理指导。为了实现这一总体目标,我们计划制定一系列专家共识,涵盖15种主要非传染性疾病,针对中国普通人群的健康风险管理。这些共识的目的是(1)确定并推荐适合中国人群的风险评估方法;(2)通过整合当前最佳证据和专家意见,为预防主要非传染性疾病提出建议。
■对于每个专家共识,我们将成立一个由40至50名成员组成的共识工作组。共识问题将通过整合文献综述来制定,专家意见,和在线调查。系统评价将被视为主要证据来源。如果没有符合条件的系统审查,我们会进行新的系统审查,方法学质量低,或现有的系统评价已发表超过3年。我们将根据分级方法评估证据质量并提出建议。共识将根据医疗保健实践指南报告项目(右)进行报告。