关键词: IBD PSC immunosuppression liver transplantation retransplantation

Mesh : Humans Liver Transplantation Cholangitis, Sclerosing / complications surgery Risk Factors Immunosuppressive Agents / therapeutic use Inflammatory Bowel Diseases / complications surgery

来  源:   DOI:10.3389/ti.2023.11729   PDF(Pubmed)

Abstract:
Primary sclerosing cholangitis (PSC) is the classical hepatobiliary manifestation of inflammatory bowel disease (IBD) and a lead indication for liver transplantation (LT) in the western world. In this article, we present a Consensus Statement on LT practice, developed by a dedicated Guidelines\' Taskforce of the European Society of Organ Transplantation (ESOT). The overarching goal is to provide practical guidance on commonly debated topics, including indications and timing of LT, management of bile duct stenosis in patients on the transplant waiting list, technical aspects of transplantation, immunosuppressive strategies post-transplant, timing and extension of intestinal resection and futility criteria for re-transplantation.
摘要:
原发性硬化性胆管炎(PSC)是炎症性肠病(IBD)的经典肝胆表现,是西方世界肝移植(LT)的主要指征。在这篇文章中,我们就LT实践发表共识声明,由欧洲器官移植学会(ESOT)的专门指南工作组开发。首要目标是就普遍辩论的主题提供实际指导,包括LT的指示和时间,移植等待名单上患者胆管狭窄的处理,移植的技术方面,移植后的免疫抑制策略,肠切除的时机和延长以及再次移植的无效标准。
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