Mesh : Humans Aged Infant, Newborn Case-Control Studies Skin Epidermis Skin Aging Water

来  源:   DOI:10.1016/j.jtv.2023.09.004

Abstract:
BACKGROUND: The world population is growing rapidly and skin problems such as skin tears (STs) are more common in aging skin due to changes in the epidermis and dermis. Identification of ageing related skin properties, which are risk factors for STs, is essential for the development of ST prevention protocols.
OBJECTIVE: The aim of this study was to reveal the skin properties related to epidermal function and dermal associated with STs.
METHODS: A prospective case-control study was conducted with a sample of 36 older adults, 18 participants with ST and 18 participants without ST, in two elderly care centers. Tewameter TM 210 was used to measure transepidermal water loss, the Sebumeter SM810 was used to measure sebum, and Cutometer Dual MPA 580 was used to measure skin viscoelasticity (R0-R9). The differences of skin properties between groups were analyzed using the independent t-test and Mann-Whitney U test.
RESULTS: The case group had a mean age of 77,17 ± 9,7 and the control group had a mean age of 75,33 ± 6,8. It was determined that there were more ecchymosis (p < 0.000), hematoma (p = 0.008), and ST history (p = 0.001) in the case group. Older adults in the case group were more frail than the control group (p = 0.044). Regarding the score of the skin properties, the case group showed that the TEWL levels of the older adults in the case group were lower (p = 0.031) compared to the control groups. There was a significant difference between the groups and R0, R2, R5, and R7. While R0 was higher in the case group, R2, R5, and R7 were lower than the control group.
CONCLUSIONS: Older adults with ST showed differences in skin properties compared to those without ST, especially transepidermal water loss, and viscoelasticity (R0, R2, R5, R7). The results of this study suggest that some changes in skin properties may be a risk factor for STs.
摘要:
背景:世界人口正在快速增长,由于表皮和真皮的变化,诸如皮肤撕裂(ST)之类的皮肤问题在老化皮肤中更为常见。识别与老化相关的皮肤特性,这是性病的危险因素,对于ST预防方案的制定至关重要。
目的:本研究的目的是揭示与STs相关的表皮功能和真皮的皮肤特性。
方法:对36名老年人进行了前瞻性病例对照研究,18名ST和18名没有ST的参与者,在两个老人护理中心。TewameterTM210用于测量经皮水分损失,SebubeterSM810用于测量皮脂,和切削计双MPA580用于测量皮肤粘弹性(R0-R9)。使用独立t检验和Mann-WhitneyU检验分析各组间皮肤特性的差异。
结果:病例组的平均年龄为77,17±9,7岁,对照组的平均年龄为75,33±6,8岁。确定有更多的瘀斑(p<0.000),血肿(p=0.008),病例组的ST病史(p=0.001)。病例组中的老年人比对照组更虚弱(p=0.044)。关于皮肤属性的分数,病例组显示,与对照组相比,病例组老年人的TEWL水平较低(p=0.031).R0、R2、R5和R7组间存在显著差异。而病例组的R0较高,R2、R5和R7低于对照组。
结论:患有ST的老年人与没有ST的老年人相比,皮肤特性存在差异。尤其是经皮水分流失,和粘弹性(R0,R2,R5,R7)。这项研究的结果表明,皮肤特性的某些变化可能是STs的危险因素。
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