PDF(Pubmed)
Abstract：
The varicella-zoster virus (VZV), a member of the Herpesviridae family, causes both the initial varicella infection and subsequent zoster episodes. Disorders of the eighth cranial nerve are common in people with herpes zoster oticus (HZO). We performed a review of the literature on different databases including PubMed and SCOPUS, focusing on cochlear and vestibular symptoms; 38 studies were considered in our review. A high percentage of cases of HZO provokes cochlear and vestibular symptoms, hearing loss and vertigo, whose onset is normally preceded by vesicles on the external ear. It is still under debate if the sites of damage are the inferior/superior vestibular nerves and cochlear nerves or a direct localization of the infection in the inner ear. The involvement of other contiguous cranial nerves has also been reported in a few cases. We report the case of a patient with single-side HZO presenting clinical manifestations of cochleo-vestibular damage without neurological and meningeal signs; after 15 days, the patient developed a new episode of vertigo with clinical findings of acute contralateral vestibular loss. To our knowledge, only three other such cases have been published. An autoimmune etiology may be considered to explain these findings.
摘要：
水痘-带状疱疹病毒(VZV),疱疹病毒科的一员,导致最初的水痘感染和随后的带状疱疹发作。第八脑神经的疾病在带状疱疹（HZO）患者中很常见。我们对不同数据库的文献进行了综述，包括PubMed和SCOPUS，重点关注耳蜗和前庭症状；我们的综述考虑了38项研究。高比例的HZO病例会引起耳蜗和前庭症状，听力损失和眩晕,其发作之前通常是外耳上的囊泡。损伤部位是否为前庭下/上神经和耳蜗神经或内耳感染的直接定位仍在争论中。在少数情况下，也有其他连续颅神经受累的报道。我们报告了一例单侧HZO患者，临床表现为无神经和脑膜体征的耳蜗前庭损伤；15天后，患者出现新的眩晕发作，临床表现为急性对侧前庭丢失。据我们所知,只有另外三个这样的案例被公布。可以考虑自身免疫病因来解释这些发现。
