PDF(Pubmed)
Abstract：
People with schizophrenia often delay treatment. This issue is not fully understood, particularly in low-and middle-income countries. This study aimed to elucidate the prevalence, risk factors and multiple outcomes of treatment delay in schizophrenia in a Chinese metropolis.
A two-stage whole cluster sampling survey was conducted in Beijing, China in 2020. A total of 1,619 patients with schizophrenia were included. Heterogeneity between groups and the changing trend of treatment delay were presented. Regression modelling methods were used to examine both the risk factors for treatment delay and related outcomes at individual and family levels.
The median treatment delay for schizophrenia was 89 days (about 13 weeks). 49.35% surveyed patients delayed treatment for more than three months. Early age of onset, low level of education, living in well developed districts were important risk factors. Treatment delay in schizophrenia was significantly associated with patients\' poor medication adherence, comorbidity status and poor social functioning. It also increased the negative impact of the illness on families.
This study accumulated evidence of treatment delay in schizophrenia in China. It occurs even in the metropolis where mental health resources are relatively adequate. Further targeted interventions to raise public awareness should be crucial to reduce treatment delay.
A two-stage whole cluster sampling survey was conducted in Beijing, China in 2020. A total of 1,619 patients with schizophrenia were included. Heterogeneity between groups and the changing trend of treatment delay were presented. Regression modelling methods were used to examine both the risk factors for treatment delay and related outcomes at individual and family levels.
The median treatment delay for schizophrenia was 89 days (about 13 weeks). 49.35% surveyed patients delayed treatment for more than three months. Early age of onset, low level of education, living in well developed districts were important risk factors. Treatment delay in schizophrenia was significantly associated with patients\' poor medication adherence, comorbidity status and poor social functioning. It also increased the negative impact of the illness on families.
This study accumulated evidence of treatment delay in schizophrenia in China. It occurs even in the metropolis where mental health resources are relatively adequate. Further targeted interventions to raise public awareness should be crucial to reduce treatment delay.
摘要：
背景：精神分裂症患者经常延迟治疗。这个问题还没有完全理解，特别是在中低收入国家。这项研究旨在阐明患病率，中国大都市精神分裂症治疗延迟的危险因素和多重结局。
方法：在北京进行了两阶段整群抽样调查，2020年的中国。共纳入1,619例精神分裂症患者。提出了组间的异质性和治疗延迟的变化趋势。回归模型方法用于检查个人和家庭水平的治疗延迟和相关结局的危险因素。
结果：精神分裂症的中位治疗延迟为89天（约13周）。49.35%的受访患者延迟治疗超过三个月。发病年龄早,教育水平低,生活在发达地区是重要的危险因素。精神分裂症的治疗延迟与患者服药依从性差显著相关，合并症状态和不良的社会功能。这也增加了疾病对家庭的负面影响。
结论：本研究积累了中国精神分裂症治疗延迟的证据。即使在心理健康资源相对充足的大都市也会发生这种情况。提高公众意识的进一步有针对性的干预措施对于减少治疗延误至关重要。
方法：在北京进行了两阶段整群抽样调查，2020年的中国。共纳入1,619例精神分裂症患者。提出了组间的异质性和治疗延迟的变化趋势。回归模型方法用于检查个人和家庭水平的治疗延迟和相关结局的危险因素。
结果：精神分裂症的中位治疗延迟为89天（约13周）。49.35%的受访患者延迟治疗超过三个月。发病年龄早,教育水平低,生活在发达地区是重要的危险因素。精神分裂症的治疗延迟与患者服药依从性差显著相关，合并症状态和不良的社会功能。这也增加了疾病对家庭的负面影响。
结论：本研究积累了中国精神分裂症治疗延迟的证据。即使在心理健康资源相对充足的大都市也会发生这种情况。提高公众意识的进一步有针对性的干预措施对于减少治疗延误至关重要。
