PDF(Pubmed)
Abstract：
The purpose of this article is to provide an overview of white light colon capsule endoscopy\'s current clinical application, concentrating on its most recent developments. Second-generation colon capsule endoscopy (CCE2) is approved by the FDA for use as an adjunctive test in patients with incomplete colonoscopy and within Europe in patients at average risk, those with incomplete colonoscopies or those unwilling to undergo conventional colonoscopies. Since the publication of European Society of GI Endoscopy guidelines on the use of CCE, there has been a significant increase in comparative studies on the diagnostic yield of CCE. This paper discusses CCE2 in further detail. It explains newly developed colon capsule system and the current status on the use of CCE, it also provides a comprehensive summary of systematic reviews on the implementation of CCE in colorectal cancer screening from a methodological perspective. Patients with ulcerative colitis can benefit from CCE2 in terms of assessing mucosal inflammation. As part of this review, performance of CCE2 for assessing disease severity in ulcerative colitis is compared with colonoscopy. Finally, an assessment if CCE can become a cost-effective clinical service overall.
摘要：
本文旨在对白光结肠胶囊内镜的临床应用现状进行综述,专注于其最新发展。第二代结肠胶囊内镜（CCE2）被FDA批准用于结肠镜检查不完全患者和欧洲平均风险患者的辅助检查。结肠镜检查不完全或不愿意接受常规结肠镜检查的人。自从欧洲胃肠道内窥镜学会关于使用CCE的指南发表以来，CCE诊断率的比较研究显著增加.本文进一步详细讨论了CCE2。它解释了新开发的结肠胶囊系统和CCE的使用现状，它还从方法学角度全面总结了CCE在结直肠癌筛查中的实施情况.在评估粘膜炎症方面，溃疡性结肠炎患者可以从CCE2中受益。作为这次审查的一部分，CCE2评估溃疡性结肠炎疾病严重程度的表现与结肠镜检查比较.最后,评估CCE是否可以成为具有成本效益的临床服务。
