Abstract：
UNASSIGNED: Skeletal growth arrest lines (GAL) are transverse lines of metaphyseal radiodensity accompanying episodic severe physiological stress. They are poorly described in fetal remains.
UNASSIGNED: We searched our autopsy practice for instances of fetal GAL in post mortem radiology, and correlated them with long bone histology and placental pathology. We describe the appearance, distribution, and pathology of GAL in a cohort of fetal autopsies, and compare the placental pathology accompanying GAL to the placental pathology of asymmetrical growth restriction (AGR) in the same time period.
UNASSIGNED: In 2108 consecutive fetal post mortems, we found 20 cases with GAL. About 16 were in singletons with AGR. In these 16, the distribution of placental pathologies was similar to a contemporaneous cohort of 113 cases with AGR. Of the remaining 4, two twins out of 9 sets of monochorionic twins with AGR demonstrated GAL. One case of GAL had symmetrical growth restriction with cytomegalovirus infection, and one case had no AGR and an old, unexplained retroplacental hemorrhage. On histology, GAL are characterized by a region of mineralized chondroid, which is variably incorporated into irregular trabecular bone.
UNASSIGNED: GALs accompany a variety of placental pathologies and twin-twin transfusion, suggesting episodic disease progression.
UNASSIGNED: We searched our autopsy practice for instances of fetal GAL in post mortem radiology, and correlated them with long bone histology and placental pathology. We describe the appearance, distribution, and pathology of GAL in a cohort of fetal autopsies, and compare the placental pathology accompanying GAL to the placental pathology of asymmetrical growth restriction (AGR) in the same time period.
UNASSIGNED: In 2108 consecutive fetal post mortems, we found 20 cases with GAL. About 16 were in singletons with AGR. In these 16, the distribution of placental pathologies was similar to a contemporaneous cohort of 113 cases with AGR. Of the remaining 4, two twins out of 9 sets of monochorionic twins with AGR demonstrated GAL. One case of GAL had symmetrical growth restriction with cytomegalovirus infection, and one case had no AGR and an old, unexplained retroplacental hemorrhage. On histology, GAL are characterized by a region of mineralized chondroid, which is variably incorporated into irregular trabecular bone.
UNASSIGNED: GALs accompany a variety of placental pathologies and twin-twin transfusion, suggesting episodic disease progression.
摘要：
■骨骼生长停滞系（GAL）是伴随间歇性严重生理应激的干phy端放射性的横线。它们在胎儿遗骸中的描述很差。
■我们在尸检实践中搜索了验尸放射学中胎儿GAL的实例，并与长骨组织学和胎盘病理相关。我们描述了外观，分布，和一组胎儿尸检中的GAL病理学，并比较同期伴随GAL的胎盘病理与不对称生长受限（AGR）的胎盘病理。
■在2108个连续的胎儿分娩后，我们发现了20例GAL.大约有16名患有AGR的单身人士。在这16例中，胎盘病理的分布与113例AGR的同期队列相似。在其余4个中，9组带有AGR的单绒毛膜双胞胎中有两个双胞胎表现出GAL。1例GAL对称生长受限伴巨细胞病毒感染，一个案例没有AGR和一个旧的，原因不明的胎盘后出血.在组织学上，GAL的特征是矿化软骨样区域，可变地结合到不规则的小梁骨中。
■GAL伴随着各种胎盘病变和双胎输血，提示疾病进展.
■我们在尸检实践中搜索了验尸放射学中胎儿GAL的实例，并与长骨组织学和胎盘病理相关。我们描述了外观，分布，和一组胎儿尸检中的GAL病理学，并比较同期伴随GAL的胎盘病理与不对称生长受限（AGR）的胎盘病理。
■在2108个连续的胎儿分娩后，我们发现了20例GAL.大约有16名患有AGR的单身人士。在这16例中，胎盘病理的分布与113例AGR的同期队列相似。在其余4个中，9组带有AGR的单绒毛膜双胞胎中有两个双胞胎表现出GAL。1例GAL对称生长受限伴巨细胞病毒感染，一个案例没有AGR和一个旧的，原因不明的胎盘后出血.在组织学上，GAL的特征是矿化软骨样区域，可变地结合到不规则的小梁骨中。
■GAL伴随着各种胎盘病变和双胎输血，提示疾病进展.
