Abstract：
UNASSIGNED: Faecal microbiota transplantation (FMT) has high efficacy against recurrent Clostridioides difficile infection (CDI). Despite the increasing use of this therapy, the delay between diagnosis and treatment is excessive. Furthermore, donor selection is an important and time-consuming process.
UNASSIGNED: We reviewed patients who underwent FMT for recurrent CDI at the CHU Charleroi Hospital between 2015 and 2022. The general context, type of administration, adverse events, and donor selection were reported. FMT was conducted using gastroduodenoscopy, colonoscopy, and enema with either fresh or frozen material.
UNASSIGNED: Ten patients with multiple comorbidities were treated by FMT. Seven patients were cured after one procedure. One patient was successfully cured after a change to an unrelated donor, and preliminary efficacy was established.
UNASSIGNED: FMT is an effective treatment that should be considered during the earlier phases of treatment. Stool donors should be thoroughly screened for infectious diseases and other criteria related to microbiota composition.
UNASSIGNED: We reviewed patients who underwent FMT for recurrent CDI at the CHU Charleroi Hospital between 2015 and 2022. The general context, type of administration, adverse events, and donor selection were reported. FMT was conducted using gastroduodenoscopy, colonoscopy, and enema with either fresh or frozen material.
UNASSIGNED: Ten patients with multiple comorbidities were treated by FMT. Seven patients were cured after one procedure. One patient was successfully cured after a change to an unrelated donor, and preliminary efficacy was established.
UNASSIGNED: FMT is an effective treatment that should be considered during the earlier phases of treatment. Stool donors should be thoroughly screened for infectious diseases and other criteria related to microbiota composition.
摘要：
■粪便微生物群移植（FMT）对复发性艰难梭菌感染（CDI）具有很高的疗效。尽管越来越多地使用这种疗法，诊断和治疗之间的延迟过大。此外，供体选择是一个重要而耗时的过程。
■我们回顾了2015年至2022年间在CHUCharleroi医院接受FMT治疗复发性CDI的患者。一般背景，管理类型,不良事件,并报告了供体选择。FMT是使用胃十二指肠镜检查进行的，结肠镜检查,用新鲜或冷冻材料灌肠。
■10例合并多种疾病的患者接受FMT治疗。7例患者在一次手术后治愈。一名患者在改为无关供体后成功治愈，并初步确立了疗效。
■FMT是一种有效的治疗方法，应在治疗的早期阶段加以考虑。粪便供体应彻底筛查传染病和其他与微生物群组成相关的标准。
■我们回顾了2015年至2022年间在CHUCharleroi医院接受FMT治疗复发性CDI的患者。一般背景，管理类型,不良事件,并报告了供体选择。FMT是使用胃十二指肠镜检查进行的，结肠镜检查,用新鲜或冷冻材料灌肠。
■10例合并多种疾病的患者接受FMT治疗。7例患者在一次手术后治愈。一名患者在改为无关供体后成功治愈，并初步确立了疗效。
■FMT是一种有效的治疗方法，应在治疗的早期阶段加以考虑。粪便供体应彻底筛查传染病和其他与微生物群组成相关的标准。
