关键词: Fire needle Mycobacterium chelonae Photodynamic therapy

Mesh : Humans Mycobacterium chelonae Mycobacterium Infections, Nontuberculous / drug therapy Photochemotherapy / methods Photosensitizing Agents / therapeutic use Anti-Bacterial Agents / therapeutic use

来  源:   DOI:10.1016/j.pdpdt.2023.103836

Abstract:
Mycobacterium chelonae is a non-tuberculous mycobacteria, which can cause skin infectious granuloma through cosmetic injection. This disease\'s treatment requires a combination of sensitive antibiotics and a lengthy treatment cycle. Photodynamic therapy is still effective for patients who are unwilling to take antibiotics orally. In this case, we successfully used fire needle combined with photodynamic therapy to treat skin infectious granulomatosis caused by Mycobacterium chelonei, and achieved satisfactory results. We used fire needle to pretreat cysts and nodules, which improved the diffusion and absorption of locally applied photosensitizers and enhanced the efficacy of photodynamic therapy. However, additional clinical research is necessary to determine the efficacy and safety of fire needle combined with photodynamic therapy for cutaneous infectious granulomatosis.
摘要:
龟分枝杆菌是一种非结核分枝杆菌,通过化妆品注射可引起皮肤感染性肉芽肿。这种疾病的治疗需要敏感的抗生素和漫长的治疗周期的组合。光动力疗法对于不愿意口服抗生素的患者仍然有效。在这种情况下,采用火针联合光动力疗法成功治疗龟分枝杆菌引起的皮肤感染性肉芽肿,取得了令人满意的效果。我们用火针预处理囊肿和结节,改善了局部应用光敏剂的扩散和吸收,增强了光动力疗法的功效。然而,需要进一步的临床研究来确定火针联合光动力疗法治疗皮肤感染性肉芽肿的有效性和安全性。
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