Abstract：
Sleep disordered breathing is commonly treated with positive airway pressure therapy. Positive airway pressure therapy is delivered via a tight-fitting mask with common side effects including: leak, ineffective treatment, residual sleep disordered breathing, eye irritation, nasal congestion, pressure ulcers and poor concordance with therapy. This systematic review and meta-analysis aimed to identify the effectiveness of current treatment strategies for managing side effects associated with positive airway pressure therapy. Five databases were searched and 10,809 articles were screened, with 36 articles included in the review. Studies investigated: dressings, nasal spray/douche, chin straps, heated humidification and interfaces. No intervention either improved or detrimentally affected: positive airway pressure concordance, Epworth Sleepiness Score, residual apnoea hypopnea index or interface leak. The review was limited by study heterogeneity, particularly for outcome measures. Additionally, patient demographics were not reported, making it difficult to apply the findings to a broad clinical population. This review highlights the paucity of evidence supporting treatment strategies to manage side effects of positive airway pressure therapy.
摘要：
睡眠呼吸紊乱通常采用气道正压治疗。气道正压通气治疗是通过一个紧密配合的面罩提供的，常见的副作用包括：泄漏，无效治疗,残余睡眠呼吸紊乱，眼睛刺激,鼻塞,压疮与治疗不一致。本系统评价和荟萃分析旨在确定当前治疗策略在控制与气道正压治疗相关的副作用方面的有效性。检索了5个数据库,筛选了10809篇,审查中包括36篇文章。调查的研究：敷料，喷鼻剂/冲洗器,下巴带,加热加湿和接口。没有干预改善或受到不利影响：气道正压一致，Epworth嗜睡评分,残余的呼吸暂停低通气指数或界面渗漏。这篇综述受到研究异质性的限制，特别是结果措施。此外,未报告患者人口统计学，这使得很难将研究结果应用于广泛的临床人群。这篇综述强调了缺乏支持治疗策略来管理气道正压通气治疗副作用的证据。
