关键词: Mesoamerica Teotihuacan food habit maize dependent mitogenome sequence

Mesh : Humans Genome, Mitochondrial Body Remains Isotopes Diet DNA, Mitochondrial / genetics

来  源:   DOI:10.1080/03014460.2023.2261844

Abstract:
UNASSIGNED: The Teotihuacan civilisation was the largest one in ancient Mesoamerica. The Teotihuacan city was born in the north-eastern Basin of Mexico around the second century BC, reached its peak in the fourth century AD, and had cultural influence throughout Mesoamerica. At its peak, the size of the city reached more than 20 km2, and the total population is estimated to have increased from 100,000 to 200,000. However, knowledge of the genetic background of the Teotihuacan people is still limited.
UNASSIGNED: We aimed to determine the mitogenome sequences of the Teotihuacan human remains and compare the ancient and present Mesoamericans. In addition, we aimed to identify the food habits of ancient Teotihuacans.
UNASSIGNED: We determined the mitogenome sequences of human remains dated to 250-636 cal AD using target enrichment-coupled next generation sequencing. We also performed stable isotope analysis.
UNASSIGNED: We successfully obtained nearly full-length sequences newly unearthed from a civilian dwelling in the Teotihuacan site. Teotihuacan mitochondrial DNA was classified into the haplogroups in present and ancient Mesoamericans. In addition, Teotihuacan individuals had a diet dependent on C4 plants such as maize.
UNASSIGNED: Genetic diversity varied among the Teotihuacans.
摘要:
特奥蒂瓦坎文明是古代中美洲最大的文明。特奥蒂瓦坎市大约在公元前2世纪出生在墨西哥东北部盆地,在公元四世纪达到顶峰,并在整个中美洲产生了文化影响。在它的巅峰,城市面积达到20多平方公里,总人口估计从10万增加到20万。然而,对Teotihuacan人的遗传背景的了解仍然有限。
我们的目的是确定特奥蒂瓦坎人类遗骸的有丝分裂基因组序列,并比较古代和现在的中美洲人。此外,我们的目的是确定古代特奥蒂瓦坎的饮食习惯。
我们使用靶标富集偶联的下一代测序确定了可追溯到250-636calAD的人类遗骸的有丝分裂基因组序列。我们还进行了稳定同位素分析。
我们成功地从特奥蒂瓦坎遗址的一个平民住宅中获得了新出土的几乎全长序列。Teotihuacan线粒体DNA在当今和古代中美洲人中被分为单倍群。此外,Teotihuacan个体的饮食依赖于C4植物,例如玉米。
茶果族的遗传多样性各不相同。
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