A rare case of inflammatory myofibroblastic tumor of the bladder with local invasion of the cervix and right ovary.

罕见的膀胱炎性肌纤维母细胞瘤 ， 局部侵犯子宫颈和右卵巢。

• 发表时间: 2023 Nov
• 来源期刊: Urol Case Rep
• DOI: 10.1016/j.eucr.2023.102576
• PMID: 37811542
• 文章类型: Case Reports
• 作者列表: Neuenschwander L,Britt G,Young A,Pearce S

关键词: Inflammatory myofibroblastic tumor; Local invasion; Primary bladder tumor; Rare neoplasm

Abstract

Inflammatory myofibroblastic tumors (IMT) are rare spindle cell neoplasms derived from mesenchymal cells. Primary genitourinary IMTs share morphological and molecular features with various malignant spindle cell sarcomas, which introduces a diagnostic challenge. We present the case of a 50-year-old female who was referred for evaluation of hematuria and nonspecific urinary symptoms and was found to have a mass originating from the urinary bladder that involved the cervix and right ovary. Transurethral resection of bladder tumor (TURBT) and immunohistochemical analysis revealed an IMT. To our knowledge, this is the first documented case of primary genitourinary IMT with cervical and ovarian involvement.

摘要

炎性肌纤维母细胞瘤(IMT)是来源于间充质细胞的罕见梭形细胞肿瘤。原发性泌尿生殖系统IMT与各种恶性梭形细胞肉瘤具有相同的形态学和分子特征，这带来了诊断挑战。我们介绍了一名50岁女性的病例，该女性被转诊以评估血尿和非特异性泌尿症状，并被发现有源自膀胱的肿块，累及子宫颈和右卵巢。经尿道膀胱肿瘤切除术（TURBT）和免疫组织化学分析显示IMT。据我们所知,这是记录的首例原发性泌尿生殖系统IMT伴宫颈和卵巢受累的病例.