UNASSIGNED: A thorough search was conducted across PubMed/Medline, Hinari, Cochrane Library, and Google Scholar to identify relevant studies. The pooled odds ratio was estimated using the random effect model. The heterogeneity among the included studies was evaluated using the I2 and Cochrane Q-statistics tests. Egger\'s tests used to assess publication bias.
UNASSIGNED: A total of 19 studies comprising 6190 study participants were included. Neonatal sepsis was positively associated with several factors, namely: prolonged premature rupture of membrane (OR: 3.85, 95% CI: 2.31-6.42), low first minute APGAR score (OR: 3.74, 95% CI: 1.29-10.81), low fifth minute APGAR score (OR: 4.17, 95% CI: 1.76-9.91), delayed initiation of breastfeeding (OR: 3.41, 95% CI: 2.18-5.36), and infection of the maternal urinary tract (OR: 3.17, 95% CI: 1.87-5.35).
UNASSIGNED: Duration of rupture of membrane, APGAR score, time of initiation of breastfeeding, and urinary tract infection have a role in the development of neonatal sepsis.
■在PubMed/Medline进行了彻底的搜索,Hinari,科克伦图书馆,和谷歌学者确定相关研究。使用随机效应模型估计合并比值比。使用I2和CochraneQ统计检验评估纳入研究的异质性。Egger的测试用于评估发表偏差。
■共纳入19项研究,包括6190名研究参与者。新生儿败血症与几个因素呈正相关,即:延长胎膜早破(OR:3.85,95%CI:2.31-6.42),第一分钟APGAR得分低(OR:3.74,95%CI:1.29-10.81),第五分钟APGAR得分低(OR:4.17,95%CI:1.76-9.91),母乳喂养延迟开始(OR:3.41,95%CI:2.18-5.36),和产妇尿路感染(OR:3.17,95%CI:1.87-5.35)。
■膜破裂持续时间,APGAR评分,开始母乳喂养的时间,尿路感染在新生儿败血症的发生发展中起作用。