PDF(Pubmed)
Abstract：
This case report examines a rare occurrence of chronic spontaneous urticaria (CSU) following the administration of the CoronaVac vaccine for COVID-19. The patient developed persistent urticarial lesions that appeared and disappeared over an extended period after receiving the vaccine. The diagnosis of CSU was supported by histopathological examination and the close temporal correlation between symptom onset and vaccination. The discussion focuses on the immune mechanisms involved in CSU, the potential triggers of allergic reactions to COVID-19 vaccines, and the importance of further research to identify specific allergenic components. This case underscores the need for vigilance in monitoring and reporting adverse events related to COVID-19 vaccination to ensure vaccine safety and optimize public health strategies.
摘要：
该病例报告检查了在服用CoronaVacCOVID-19疫苗后罕见的慢性自发性荨麻疹（CSU）。患者出现持续性荨麻疹病变，在接种疫苗后长时间出现并消失。CSU的诊断得到了组织病理学检查以及症状发作与疫苗接种之间紧密的时间相关性的支持。讨论的重点是CSU涉及的免疫机制，对COVID-19疫苗过敏反应的潜在触发因素，以及进一步研究确定特定过敏成分的重要性。该病例强调了在监测和报告与COVID-19疫苗接种相关的不良事件时需要保持警惕，以确保疫苗安全并优化公共卫生策略。
