METHODS: This single-center study was designed as a retrospective study after obtaining ethical committee approval. The files of patients hospitalized at Ataturk University Faculty of Medicine, Erzurum, Turkey, between 2010 and 2019 and who underwent resection or liver transplantation for liver alveolar cysts were reviewed. Demographic features, laboratory parameters (complete blood count and biochemical parameters), lesion localizations and characteristics, type of surgery, intraoperative and postoperative complications (morbidity), and mortality status were evaluated by scanning patients\' files. Preoperative blood samples were taken the day before the surgery, which is the period farthest from surgical stress, to have more accurate results. By contrast, postoperative blood samples were taken on the first postoperative day when surgical stress was the highest. The differences between the morbidity groups, including NLR, PLR, and PNI, were compared.
RESULTS: Of the 172 patients in the study, 96 (55.8%) were female. The mean age of all patients was 48.51±15.57 (18-90). Perioperative complications were seen in 30 (17.4%) patients, while the morbidity and mortality rates of the study were 28.5% and 19.2%, respectively. Age, gender of patients, and preoperative laboratory parameters, including NLR, PLR, and PNI, did not affect morbidity. However, the presence of perioperative vascular injury (P=0.040) and complications (P=0.047), low postoperative lymphocyte rates (P=0.038), and high postoperative NLR were associated with increased morbidity. In addition, the mortality rate was significantly increased in patients with morbidity (P<0.001).
CONCLUSIONS: From the results of the present study, it was found that preoperative parameters did not affect morbidity, while increased postoperative NLR levels and decreased lymphocyte rates increased morbidity.
方法:这项单中心研究在获得伦理委员会批准后被设计为回顾性研究。阿塔图尔克大学医学院住院患者的档案,Erzurum,土耳其,我们对2010年至2019年期间接受肝肺泡囊肿切除或肝移植的患者进行了回顾.人口统计特征,实验室参数(全血细胞计数和生化参数),病变定位和特征,手术类型,术中和术后并发症(发病率),和死亡率状况通过扫描患者档案进行评估.手术前一天采集了术前血样,这是离手术压力最远的时期,得到更准确的结果。相比之下,在手术压力最高的术后第一天采集术后血样.发病率组之间的差异,包括NLR,PLR,PNI,进行了比较。
结果:在研究的172名患者中,96(55.8%)为女性。所有患者的平均年龄为48.51±15.57(18-90)。30例(17.4%)患者出现围手术期并发症,该研究的发病率和死亡率分别为28.5%和19.2%,分别。年龄,患者性别,和术前实验室参数,包括NLR,PLR,PNI,不影响发病率。然而,围手术期血管损伤(P=0.040)及并发症(P=0.047),术后淋巴细胞率低(P=0.038),高术后NLR与发病率增加相关。此外,发病率患者的死亡率显著增加(P<0.001)。
结论:根据本研究的结果,结果发现,术前参数不影响发病率,而术后NLR水平升高和淋巴细胞比率降低则增加了发病率。