PDF(Pubmed)
Abstract：
UNASSIGNED: To identify risk factors for loss to follow-up in periodic intravitreal anti-vascular endothelial growth factor injections for the treatment patients with diabetic macular edema, subretinal neovascularization, age-related macular degeneration, and retinal vein occlusion in a single eye center in São Paulo, Brazil.
UNASSIGNED: This was a retrospective longitudinal study that gathered information from 992 patients who required intravitreal anti-vascular endothelial growth factor drugs over 6 months. The authors included age, eye disease, laterality, monthly income, distance, and payment mode as risk factors.
UNASSIGNED: Two hundred and seventy patients (29.93%) were lost to follow-up. Multivariate analysis showed age, monthly income, eye involvement, and type of medical assistance independently associated with loss to follow-up. The odds of loss to follow-up were greater among older patients than those less than 50 years (reference), p < 0.001. The odds of loss to follow-up were greater among patients who received unilateral treatment than those who received bilateral injections (p = 0.013). Concerning gross monthly income, there were no differences in the odds of the four salary strata; the data also indicate an absence of difference in the three strata of patients\' distance to the clinic. Considering the diagnosis, only age-related macular degeneration showed greater odds of loss to follow-up (p = 0.016). Finally, the data suggest greater odds of loss to follow-up in private patients than in those on a health care plan (p < 0.001).
UNASSIGNED: Loss to follow-up is paramount because many patients may remain unassisted concerning their eye diseases. Identifying the risk factors is crucial to enforcing measures to increase adherence and the long-term success of the treatment.
UNASSIGNED: This was a retrospective longitudinal study that gathered information from 992 patients who required intravitreal anti-vascular endothelial growth factor drugs over 6 months. The authors included age, eye disease, laterality, monthly income, distance, and payment mode as risk factors.
UNASSIGNED: Two hundred and seventy patients (29.93%) were lost to follow-up. Multivariate analysis showed age, monthly income, eye involvement, and type of medical assistance independently associated with loss to follow-up. The odds of loss to follow-up were greater among older patients than those less than 50 years (reference), p < 0.001. The odds of loss to follow-up were greater among patients who received unilateral treatment than those who received bilateral injections (p = 0.013). Concerning gross monthly income, there were no differences in the odds of the four salary strata; the data also indicate an absence of difference in the three strata of patients\' distance to the clinic. Considering the diagnosis, only age-related macular degeneration showed greater odds of loss to follow-up (p = 0.016). Finally, the data suggest greater odds of loss to follow-up in private patients than in those on a health care plan (p < 0.001).
UNASSIGNED: Loss to follow-up is paramount because many patients may remain unassisted concerning their eye diseases. Identifying the risk factors is crucial to enforcing measures to increase adherence and the long-term success of the treatment.
摘要：
■为了确定糖尿病性黄斑水肿患者定期玻璃体内注射抗血管内皮生长因子治疗失败的危险因素，视网膜下新生血管,年龄相关性黄斑变性,圣保罗的一个眼睛中心的视网膜静脉阻塞，巴西。
■这是一项回顾性纵向研究，收集了992名需要玻璃体内抗血管内皮生长因子药物治疗6个月的患者的信息。作者包括年龄，眼病,偏侧性,月收入,距离,和支付方式作为风险因素。
■二百七十例患者（29.93％）失去了随访。多变量分析显示年龄，月收入,眼睛受累,和医疗援助类型与随访失败独立相关。与50岁以下的患者相比，老年患者失去随访的可能性更大（参考），p<0.001。与接受双侧注射的患者相比，接受单侧治疗的患者失去随访的可能性更大（p=0.013）。关于月总收入，这四个工资阶层的几率没有差异；数据还表明，这三个阶层的患者到诊所的距离没有差异。考虑到诊断，只有年龄相关性黄斑变性患者失访的几率较大(p=0.016).最后,数据表明,与接受医疗保健计划的患者相比,私人患者失访的几率更大(p<0.001).
■失去随访是至关重要的，因为许多患者可能仍然没有关于他们的眼病。识别风险因素对于执行增加依从性和治疗长期成功的措施至关重要。
■这是一项回顾性纵向研究，收集了992名需要玻璃体内抗血管内皮生长因子药物治疗6个月的患者的信息。作者包括年龄，眼病,偏侧性,月收入,距离,和支付方式作为风险因素。
■二百七十例患者（29.93％）失去了随访。多变量分析显示年龄，月收入,眼睛受累,和医疗援助类型与随访失败独立相关。与50岁以下的患者相比，老年患者失去随访的可能性更大（参考），p<0.001。与接受双侧注射的患者相比，接受单侧治疗的患者失去随访的可能性更大（p=0.013）。关于月总收入，这四个工资阶层的几率没有差异；数据还表明，这三个阶层的患者到诊所的距离没有差异。考虑到诊断，只有年龄相关性黄斑变性患者失访的几率较大(p=0.016).最后,数据表明,与接受医疗保健计划的患者相比,私人患者失访的几率更大(p<0.001).
■失去随访是至关重要的，因为许多患者可能仍然没有关于他们的眼病。识别风险因素对于执行增加依从性和治疗长期成功的措施至关重要。
