PDF(Pubmed)
Abstract：
UNASSIGNED: Regional cerebral oxygen saturation (rSO2) is linked with blood pressure. This study evaluated the influence of perioperative rSO2 monitoring on the prognosis of ischemic Moyamoya disease (MMD) patients undergoing anastomosis surgery.
UNASSIGNED: In this prospective cohort, patients with unilateral ischemic MMD of Suzuki stage ≥3 were included. The decision of rSO2 was made by the clinician and the patient. The rSO2 group maintained intraoperative rSO2 levels through the modulation of blood pressure, inhaled oxygen concentration, carbon dioxide in arterial blood, and red blood cell transfusion. The non-rSO2 group used conventional anesthesia practices. Perioperative mean arterial pressure (MAP), rSO2 values, neurological complications, and postoperative results were assessed.
UNASSIGNED: A total of 75 eligible patients were categorized into a rSO2 monitoring group (n = 30) and a non-rSO2 monitoring group (n = 45). For the rSO2 group, the preoperative rSO2 was significantly lower on the affected side (P < 0.05). After anastomosis, this value notably increased (P = 0.01). A moderate relationship was observed between perioperative rSO2 and MAP before, during, and after surgery, with correlation coefficients (r) of 0.536, 0.502, and 0.592 (P < 0.05). Post-surgery MAP levels differed between the groups, with the rSO2 group showing decreased levels compared to pre-surgery and the non-rOS2 group displaying elevated levels. Notably, the rSO2 group reported shorter hospitalizations and decreased neurological complications. Patients with a hypertension history found postoperative MAP influencing hospital stay duration.
UNASSIGNED: Perioperative rSO2 surveillance enhanced cerebral perfusion and minimized postoperative complications in ischemic MMD patients. Thus, rSO2 monitoring is advocated for MMD patients undergoing vascular anastomosis.
UNASSIGNED: In this prospective cohort, patients with unilateral ischemic MMD of Suzuki stage ≥3 were included. The decision of rSO2 was made by the clinician and the patient. The rSO2 group maintained intraoperative rSO2 levels through the modulation of blood pressure, inhaled oxygen concentration, carbon dioxide in arterial blood, and red blood cell transfusion. The non-rSO2 group used conventional anesthesia practices. Perioperative mean arterial pressure (MAP), rSO2 values, neurological complications, and postoperative results were assessed.
UNASSIGNED: A total of 75 eligible patients were categorized into a rSO2 monitoring group (n = 30) and a non-rSO2 monitoring group (n = 45). For the rSO2 group, the preoperative rSO2 was significantly lower on the affected side (P < 0.05). After anastomosis, this value notably increased (P = 0.01). A moderate relationship was observed between perioperative rSO2 and MAP before, during, and after surgery, with correlation coefficients (r) of 0.536, 0.502, and 0.592 (P < 0.05). Post-surgery MAP levels differed between the groups, with the rSO2 group showing decreased levels compared to pre-surgery and the non-rOS2 group displaying elevated levels. Notably, the rSO2 group reported shorter hospitalizations and decreased neurological complications. Patients with a hypertension history found postoperative MAP influencing hospital stay duration.
UNASSIGNED: Perioperative rSO2 surveillance enhanced cerebral perfusion and minimized postoperative complications in ischemic MMD patients. Thus, rSO2 monitoring is advocated for MMD patients undergoing vascular anastomosis.
摘要：
■局部脑氧饱和度（rSO2）与血压有关。本研究评估了围手术期rSO2监测对接受吻合手术的缺血性烟雾病（MMD）患者预后的影响。
■在这个前瞻性队列中，包括Suzuki分期≥3的单侧缺血性MMD患者.rSO2的决定由临床医生和患者做出。rSO2组通过调节血压维持术中rSO2水平，吸入氧气浓度，动脉血中的二氧化碳，和红细胞输血.非rSO2组采用常规麻醉方法。围手术期平均动脉压(MAP),rSO2值，神经系统并发症,并对术后结果进行评估。
■共有75名符合条件的患者被分为rSO2监测组（n=30）和非rSO2监测组（n=45）。对于rSO2组，患侧术前rSO2明显降低(P<0.05)。吻合后,该值显著增加(P=0.01)。围手术期rSO2和MAP之间观察到中度关系，during,手术后,相关系数(r)分别为0.536、0.502、0.592(P<0.05)。术后MAP水平不同，与手术前相比，rSO2组显示出降低的水平，而非rOS2组显示出升高的水平。值得注意的是,rSO2组报告住院时间缩短,神经系统并发症减少.有高血压病史的患者发现术后MAP会影响住院时间。
■围手术期rSO2监测可增强缺血性MMD患者的脑灌注并减少术后并发症。因此，对于接受血管吻合的MMD患者，提倡进行rSO2监测。
■在这个前瞻性队列中，包括Suzuki分期≥3的单侧缺血性MMD患者.rSO2的决定由临床医生和患者做出。rSO2组通过调节血压维持术中rSO2水平，吸入氧气浓度，动脉血中的二氧化碳，和红细胞输血.非rSO2组采用常规麻醉方法。围手术期平均动脉压(MAP),rSO2值，神经系统并发症,并对术后结果进行评估。
■共有75名符合条件的患者被分为rSO2监测组（n=30）和非rSO2监测组（n=45）。对于rSO2组，患侧术前rSO2明显降低(P<0.05)。吻合后,该值显著增加(P=0.01)。围手术期rSO2和MAP之间观察到中度关系，during,手术后,相关系数(r)分别为0.536、0.502、0.592(P<0.05)。术后MAP水平不同，与手术前相比，rSO2组显示出降低的水平，而非rOS2组显示出升高的水平。值得注意的是,rSO2组报告住院时间缩短,神经系统并发症减少.有高血压病史的患者发现术后MAP会影响住院时间。
■围手术期rSO2监测可增强缺血性MMD患者的脑灌注并减少术后并发症。因此，对于接受血管吻合的MMD患者，提倡进行rSO2监测。
