关键词: Acral lentiginous melanoma bone metastasis case report cutaneous melanoma

Mesh : Humans Male Aged, 80 and over Melanoma / pathology Skin Neoplasms / pathology Skin / pathology Foot / pathology Bone Neoplasms / diagnosis pathology Melanoma, Cutaneous Malignant

来  源:   DOI:10.11604/pamj.2023.45.141.40508   PDF(Pubmed)

Abstract:
Acral lentiginous melanoma (ALM) is a type of melanoma that is traditionally seen on the soles of the feet, palms of the hand, and under the fingernails or toenails. It is the least frequently diagnosed melanoma among the four histologic subtypes of cutaneous melanoma, accounting for less than 5% of all cases. ALM is frequently diagnosed at late stages and has higher incidences in non-white populations in relation to the other forms of cutaneous malignant melanoma. The most common sites of metastases in melanoma are the skin and subcutaneous tissue followed by lung, liver, brain, and bone. Bone metastases from malignant melanoma usually occur in patients who already have widespread metastases. We present this paper as a unique case study of ALM lesion in an 84-year-old African American male presenting originally in the base of right fifth toe plantar aspect then found multiple bone metastases without any other organ involved.
摘要:
肢端淡色黑色素瘤(ALM)是一种传统上在脚底可见的黑色素瘤,手掌,在指甲或脚趾甲下面。它是皮肤黑色素瘤四种组织学亚型中最不常见的黑色素瘤,占所有病例的不到5%。ALM通常在晚期被诊断,并且相对于其他形式的皮肤恶性黑素瘤,在非白种人群中具有更高的发病率。黑色素瘤中最常见的转移部位是皮肤和皮下组织,其次是肺,肝脏,大脑,还有骨头.恶性黑色素瘤骨转移通常发生在已经广泛转移的患者中。我们将本文作为一名84岁的非洲裔美国男性的ALM病变的独特案例研究,最初出现在右第五脚趾足底的底部,然后发现多个骨转移而没有任何其他器官。
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