PDF(Pubmed)
Abstract：
Infective endocarditis (IE) is life-threatening and can lead to complications if left untreated. A 56-year-old gentleman presented with acute delirium, fever and rigor. Panton-Valentine leukocidin (PVL)-positive Staphylococcus aureus (S. aureus) was isolated in the blood culture and the PR interval was prolonged on the electrocardiogram (ECG). However, the transthoracic echocardiogram (TTE) and transoesophageal echocardiogram (TOE) at presentation were unremarkable with no evidence of intracardiac vegetations. Despite expedient intravenous antibiotics, an acquired ventricular septal defect (VSD) developed, which required urgent cardiothoracic surgical repair. It is imperative to consider early surgical interventions and the use of anti-toxin antibiotics in PVL-positive S. aureus IE.
摘要：
感染性心内膜炎（IE）危及生命，如果不及时治疗，可能导致并发症。一位56岁的绅士出现急性谵妄，发烧和僵硬。Panton-Valentine杀白细胞素（PVL）阳性金黄色葡萄球菌（S.金黄色葡萄球菌）在血培养物中分离，PR间隔在心电图（ECG）上延长。然而,就诊时的经胸超声心动图(TTE)和经食道超声心动图(TOE)均无明显变化,无心内植被证据.尽管有适当的静脉注射抗生素,获得性室间隔缺损(VSD),需要紧急的心胸手术修复。必须考虑早期手术干预和抗毒素抗生素在PVL阳性金黄色葡萄球菌IE中的使用。
