Abstract:
Coronaviruses (CoVs) are a significant group of pathogens that pose a serious threat to both human and animal health, with some being zoonotic and displaying frequent cross-species transmission. Human CoV-OC43 (HCoV-OC43) is one of the four common human CoVs that can cause seasonal mild to moderate respiratory diseases in humans. In this study, we identified HCoV-OC43 for the first time in two asymptomatic pet hamsters, which share a high similarity with the human-derived HCoV-OC43 strain, suggesting potential cross-species transmission of HCoV-OC43 to pet hamsters. The finding emphasizes the need to strengthen pathogen monitoring of livestock and pets in close contact with humans to provide early warning of public safety.
摘要:
冠状病毒(CoV)是一类重要的病原体,对人类和动物健康构成严重威胁,其中一些是人畜共患的,并显示出频繁的跨物种传播。人类CoV-OC43(HCoV-OC43)是四种常见的人类CoV之一,可引起人类季节性轻度至中度呼吸道疾病。在这项研究中,我们首次在两只无症状的宠物仓鼠中鉴定出HCoV-OC43,与人类来源的HCoV-OC43菌株有很高的相似性,提示HCoV-OC43潜在的跨物种传播给宠物仓鼠。该发现强调需要加强对与人类密切接触的牲畜和宠物的病原体监测,以提供公共安全的预警。