关键词: Creatinine ESRD hemodialysis mucocutaneous

Mesh : Male Female Humans Adult Middle Aged Cross-Sectional Studies Creatinine Quality of Life Kidney Failure, Chronic / complications therapy Renal Dialysis / adverse effects Renal Insufficiency, Chronic / complications therapy Lichen Planus

来  源:   DOI:10.4103/ijdr.IJDR_802_20

Abstract:
UNASSIGNED: Patients with end-stage renal disease (ESRD) suffer from mucocutaneous changes that could significantly impair the quality of life. We aimed this study to assess the mucocutaneous changes in hemodialysis patients and to correlate the serum creatinine to these changes.
UNASSIGNED: Data were collected from the Hemodialysis Center at Benha University. A cross-sectional study design on 130 chronic kidney disease (CKD) patients (30-60 years old, 84 males, 46 females) undergoing hemodialysis. Oral examinations were done for these patients as per the modified World Health Organization oral health survey 2013 criteria. All the mucocutaneous changes were recorded then types, distribution, and frequencies were calculated and correlated to serum creatinine.
UNASSIGNED: Mucocutaneous abnormalities were present in 100% of the studied CKD sample. We observed that pallor (76.2%), xerostomia (70%), petechiae/purpura (49.2%), altered taste (49.2%), and lip pigmentation (40.8%) were the most prevalent mucocutaneous changes among the CKD patients undergoing hemodialysis. A strong association was detected between serum creatinine and the following: abnormal lip pigmentation and lichen planus.
UNASSIGNED: There is an association between lip pigmentation and lichen planus in CKD patients and the level of serum creatinine as the higher level of serum creatinine was found in the patients with abnormal lip pigmentation and the atrophic lichen planus patients.
摘要:
患有终末期肾病(ESRD)的患者患有皮肤粘膜变化,这可能会严重损害生活质量。本研究旨在评估血液透析患者的皮肤黏膜变化,并将血清肌酐与这些变化相关联。
从Benha大学的血液透析中心收集数据。一项针对130名慢性肾脏病(CKD)患者(30-60岁,84雄性,46名女性)接受血液透析。根据修改后的世界卫生组织2013年口腔健康调查标准对这些患者进行口腔检查。记录所有粘膜皮肤变化,然后分类,分布,并计算频率并与血清肌酐相关。
在所研究的CKD样本中100%存在皮肤粘膜异常。我们观察到苍白(76.2%),口干症(70%),瘀点/紫癜(49.2%),味道改变(49.2%),在接受血液透析的CKD患者中,嘴唇色素沉着(40.8%)是最普遍的粘膜皮肤变化。血清肌酐与以下指标之间存在强烈关联:异常的嘴唇色素沉着和扁平苔藓。
CKD患者的嘴唇色素沉着与扁平苔藓和血清肌酐水平之间存在关联,因为在嘴唇色素沉着异常和萎缩性扁平苔藓患者中发现血清肌酐水平较高。
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