PDF(Pubmed)
Abstract：
UNASSIGNED: Disorders of consciousness (DOC) are neurocognitive disorders related to sharp fluctuations of attention and consciousness, while DOC is characterized by significant interindividual differences, rapid development, and a higher lethal rate.
UNASSIGNED: A 53-year-old female patient underwent general anesthesia with tracheal intubation in otoendoscopic tympanoplasty. The patient suddenly appeared moderate DOC after tracheal tube removal with K+ 3.6 (3.5-5.3 mmol/L). Based on the ancillary testing and routine laboratory workup, the possible causes of DOC, such as general anesthesia drugs and cardio cerebral events, were temporarily excluded. DOC was reversed by intravenous administration of KCl 1 g, with K+ 3.78 mmol/L. On one day after surgery, the patient occurred suddenly DOC again after intravenous guttae of 5% glucose 1000 ml, K+ 3.87 mmol/L, possibly because of her recurrent hypokalemic paralysis (HP) of past medical history. The patient\'s consciousness gradually improved after effective KCl supplementation therapy.
UNASSIGNED: DOC caused by periodic paralysis (PP) has not been reported, we speculate that hypoactive DOC is closely correlated with normokalemic periodic paralysis (NormoPP) in this case.
UNASSIGNED: A 53-year-old female patient underwent general anesthesia with tracheal intubation in otoendoscopic tympanoplasty. The patient suddenly appeared moderate DOC after tracheal tube removal with K+ 3.6 (3.5-5.3 mmol/L). Based on the ancillary testing and routine laboratory workup, the possible causes of DOC, such as general anesthesia drugs and cardio cerebral events, were temporarily excluded. DOC was reversed by intravenous administration of KCl 1 g, with K+ 3.78 mmol/L. On one day after surgery, the patient occurred suddenly DOC again after intravenous guttae of 5% glucose 1000 ml, K+ 3.87 mmol/L, possibly because of her recurrent hypokalemic paralysis (HP) of past medical history. The patient\'s consciousness gradually improved after effective KCl supplementation therapy.
UNASSIGNED: DOC caused by periodic paralysis (PP) has not been reported, we speculate that hypoactive DOC is closely correlated with normokalemic periodic paralysis (NormoPP) in this case.
摘要：
■意识障碍（DOC）是与注意力和意识的剧烈波动有关的神经认知障碍，虽然DOC的特征是显著的个体差异，快速发展,和更高的致死率。
■一名53岁女性患者在耳内镜鼓室成形术中接受了气管插管全身麻醉。患者在用K3.6（3.5-5.3mmol/L）拔除气管导管后突然出现中度DOC。根据辅助测试和常规实验室检查，DOC的可能原因，如全身麻醉药物和心脑事件，暂时被排除在外。通过静脉注射氯化钾1克，可以逆转DOC，K+3.78mmol/L手术后的一天，患者在静脉注射5%葡萄糖1000毫升后突然再次出现DOC，K+3.87mmol/L,可能是因为她的既往病史反复出现低血钾麻痹（HP）。经过有效的氯化钾补充治疗后，患者的意识逐渐改善。
■由周期性麻痹（PP）引起的DOC尚未报道，我们推测,在这种情况下,DOC活性低下与正常钾性周期性麻痹(NormoPP)密切相关.
■一名53岁女性患者在耳内镜鼓室成形术中接受了气管插管全身麻醉。患者在用K3.6（3.5-5.3mmol/L）拔除气管导管后突然出现中度DOC。根据辅助测试和常规实验室检查，DOC的可能原因，如全身麻醉药物和心脑事件，暂时被排除在外。通过静脉注射氯化钾1克，可以逆转DOC，K+3.78mmol/L手术后的一天，患者在静脉注射5%葡萄糖1000毫升后突然再次出现DOC，K+3.87mmol/L,可能是因为她的既往病史反复出现低血钾麻痹（HP）。经过有效的氯化钾补充治疗后，患者的意识逐渐改善。
■由周期性麻痹（PP）引起的DOC尚未报道，我们推测,在这种情况下,DOC活性低下与正常钾性周期性麻痹(NormoPP)密切相关.
