Abstract：
OBJECTIVE: To determine the sialendoscopy findings associated with positive findings on minor salivary gland biopsy.
METHODS: Single-center retrospective study.
METHODS: Patients ≥18 years old who underwent sialendoscopy from 2016 to 2022 and were evaluated for SS via labial minor salivary gland biopsy. Biopsy positive and negative patients were compared on the primary outcome measure of sialendoscopy findings. Data were abstracted from the sialendoscopy operative notes and included involved gland, location of ductal pathology, and the presence of scarring, stenosis, mucus plugs, webs, and dilations. Additional characteristics included demographics, presenting symptoms, caffeine or tobacco, use of drying medications, and need for additional treatments.
RESULTS: The final cohorts included 22 biopsy positive and 21 biopsy negative patients with a total of 42 glands in the biopsy positive and 37 glands in the biopsy negative groups. Biopsy positive patients were found to require dilation at the hilum and distal duct at significantly higher rates than biopsy negative patients (p < 0.0001). However, there was no statistical difference in scarring, stenosis severity, mucus, webs, or dilations between each group.
CONCLUSIONS: The outcomes of this study suggest that there are no distinct sialendoscopy findings associated with biopsy positive patients. The presence of significant distal stenosis on sialendoscopy may be associated with positive minor salivary biopsy. Other endoscopic parameters are likely more consistent with non-specific chronic sialadenitis.
METHODS: 3 Laryngoscope, 134:1183-1189, 2024.
METHODS: Single-center retrospective study.
METHODS: Patients ≥18 years old who underwent sialendoscopy from 2016 to 2022 and were evaluated for SS via labial minor salivary gland biopsy. Biopsy positive and negative patients were compared on the primary outcome measure of sialendoscopy findings. Data were abstracted from the sialendoscopy operative notes and included involved gland, location of ductal pathology, and the presence of scarring, stenosis, mucus plugs, webs, and dilations. Additional characteristics included demographics, presenting symptoms, caffeine or tobacco, use of drying medications, and need for additional treatments.
RESULTS: The final cohorts included 22 biopsy positive and 21 biopsy negative patients with a total of 42 glands in the biopsy positive and 37 glands in the biopsy negative groups. Biopsy positive patients were found to require dilation at the hilum and distal duct at significantly higher rates than biopsy negative patients (p < 0.0001). However, there was no statistical difference in scarring, stenosis severity, mucus, webs, or dilations between each group.
CONCLUSIONS: The outcomes of this study suggest that there are no distinct sialendoscopy findings associated with biopsy positive patients. The presence of significant distal stenosis on sialendoscopy may be associated with positive minor salivary biopsy. Other endoscopic parameters are likely more consistent with non-specific chronic sialadenitis.
METHODS: 3 Laryngoscope, 134:1183-1189, 2024.
摘要：
目的：确定唾液腺镜检查结果与小唾液腺活检结果阳性相关。
方法：单中心回顾性研究。
方法：2016年至2022年接受唾液酸内镜检查并通过唇小涎腺活检评估SS的年龄≥18岁患者。比较活检阳性和阴性患者的主要结果测量结果。数据从唾液酸内镜手术记录中提取，包括受累腺体，导管病理学的位置，和疤痕的存在，狭窄,粘液塞，腹板,和扩张。其他特征包括人口统计，出现症状，咖啡因或烟草，使用干燥药物，需要额外的治疗。
结果：最终队列包括22例活检阳性和21例活检阴性患者，活检阳性组共有42个腺体，活检阴性组共有37个腺体。发现活检阳性患者需要在肺门和远端导管扩张的比率明显高于活检阴性患者(p<0.0001)。然而,疤痕没有统计学差异，狭窄严重程度,粘液,腹板,或每组之间的扩张。
结论：这项研究的结果表明，活检阳性患者没有明显的唾液酸内镜检查结果。在唾液内镜检查中存在明显的远端狭窄可能与唾液小活检阳性有关。其他内镜参数可能与非特异性慢性唾液腺炎更一致。
方法：3喉镜，2023年。
方法：单中心回顾性研究。
方法：2016年至2022年接受唾液酸内镜检查并通过唇小涎腺活检评估SS的年龄≥18岁患者。比较活检阳性和阴性患者的主要结果测量结果。数据从唾液酸内镜手术记录中提取，包括受累腺体，导管病理学的位置，和疤痕的存在，狭窄,粘液塞，腹板,和扩张。其他特征包括人口统计，出现症状，咖啡因或烟草，使用干燥药物，需要额外的治疗。
结果：最终队列包括22例活检阳性和21例活检阴性患者，活检阳性组共有42个腺体，活检阴性组共有37个腺体。发现活检阳性患者需要在肺门和远端导管扩张的比率明显高于活检阴性患者(p<0.0001)。然而,疤痕没有统计学差异，狭窄严重程度,粘液,腹板,或每组之间的扩张。
结论：这项研究的结果表明，活检阳性患者没有明显的唾液酸内镜检查结果。在唾液内镜检查中存在明显的远端狭窄可能与唾液小活检阳性有关。其他内镜参数可能与非特异性慢性唾液腺炎更一致。
方法：3喉镜，2023年。
