A total of 36 patients with spinal metastasis who underwent dynamic contrast-enhanced magnetic resonance spinal perfusion imaging at Tianjin Hospital from December 2018 to December 2020 were reviewed. Subsequently, the patients underwent corresponding preoperative examination using digital subtraction angiography of the spine at the hospital and were divided into 2 groups accordingly. Differences in dynamic MRI perfusion parameters between the 2 groups were analyzed.
There were statistically significant differences between the 2 groups in the quantitative dynamic contrast-enhanced MRI perfusion parameters vascular permeability and plasma volume, as well as semi-quantitative peak enhancement and blood flow ratio parameters.
Dynamic MRI perfusion may distinguish spinal metastatic lesions with rich blood supply from those with poor blood supply and may help clinicians identify patients that can benefit from invasive spinal angiography and preoperative embolization. This technique may also provide guidance on decision taking for surgery basing on dynamic MRI perfusion parameters.
方法:回顾性分析2018年12月至2020年12月在天津医院行动态增强磁共振脊髓灌注成像的36例脊柱转移瘤患者。随后,患者在医院接受了相应的术前检查,使用数字减影血管造影对脊柱进行了检查,并将其分为两组。分析两组MRI动态灌注参数的差异。
结果:两组在定量动态增强MRI灌注参数Ktrans和VP方面有统计学差异,以及半定量峰增强和血流量比参数。
结论:动态MRI灌注可以区分血液供应丰富的脊柱转移灶和血液供应不足的脊柱转移灶,并且可以帮助临床医生识别可以从侵入性脊髓血管造影和术前栓塞术中获益的患者。该技术还可以为基于动态MRI灌注参数的手术决策提供指导。