PDF(Pubmed)
Abstract：
There is a need to close the gap between knowledge and action in health care. Effective care requires a convenient and reliable distribution process. As global internet and mobile communication increase capacity, innovative approaches to digital health education platforms and care delivery are feasible. We report the case of a young African woman who developed acute secondary amenorrhea at age 18. Subsequently, she experienced a 10-year delay in the diagnosis of the underlying cause. A global digital medical hub focused on women\'s health and secondary amenorrhea could reduce the chance of such mismanagement. Such a hub would establish more efficient information integration and exchange processes to better serve patients, family caregivers, health care providers, and investigators. Here, we show proof of concept for a global digital medical hub for women\'s health. First, we describe the physiological control systems that govern the normal menstrual cycle, and review the pathophysiology and management of secondary amenorrhea. The symptom may lead to broad and profound health implications for the patient and extended family members. In specific situations, there may be significant morbidity related to estradiol deficiency: (1) reduced bone mineral density, 2) cardiovascular disease, and 3) cognitive decline. Using primary ovarian insufficiency (POI) as the paradigm condition, the Mary Elizabeth Conover Foundation has been able to address the specific global educational needs of these women. The Foundation did this by creating a professionally managed Facebook group specifically for these women. POI most commonly presents with secondary amenorrhea. Here we demonstrate the feasibility of conducting a natural history study on secondary amenorrhea with international reach to be coordinated by a global digital medical hub. Such an approach takes full advantage of internet and mobile device communication systems. We refer to this global digital women\'s health initiative as My 28 Days®.
摘要：
有必要缩小医疗保健知识与行动之间的差距。有效的护理需要方便可靠的分配过程。随着全球互联网和移动通信容量的增加，数字健康教育平台和护理服务的创新方法是可行的。我们报告了一名年轻的非洲妇女在18岁时出现急性继发性闭经的病例。随后，她经历了10年的延迟诊断的根本原因。一个专注于女性健康和继发性闭经的全球数字医疗中心可以减少这种管理不善的机会。这样的中心将建立更有效的信息整合和交换流程，以更好地为患者服务。家庭照顾者,卫生保健提供者,和调查员。这里,我们展示了全球女性健康数字医疗中心的概念证明。首先,我们描述了控制正常月经周期的生理控制系统，并对继发性闭经的病理生理学和治疗进行综述。这种症状可能会对患者和大家庭成员产生广泛而深刻的健康影响。在特定情况下,可能存在与雌二醇缺乏相关的显著发病率:(1)骨密度降低,2）心血管疾病，3)认知能力下降。使用原发性卵巢功能不全（POI）作为范式条件，玛丽·伊丽莎白·康诺佛基金会已经能够解决这些妇女的特定全球教育需求。基金会通过专门为这些女性创建一个专业管理的Facebook小组来做到这一点。POI最常表现为继发性闭经。在这里，我们证明了由全球数字医疗中心协调进行具有国际影响力的继发性闭经自然历史研究的可行性。这种方法充分利用了互联网和移动设备通信系统。我们将这项全球数字女性健康计划称为My28Days®。
