关键词: Behçet's disease allogeneic hematopoietic stem cell transplantation autoimmunity juvenile myelomonocytic leukemia myeloid malignancy

Mesh : Female Humans Child Leukemia, Myelomonocytic, Juvenile / diagnosis therapy complications Behcet Syndrome / complications diagnosis therapy Hematopoietic Stem Cell Transplantation / methods Pathologic Complete Response

来  源:   DOI:10.1111/1756-185X.14882

Abstract:
Behçet\'s disease (BD) is a rare condition that is seldom associated with hematological malignancies. In this case report, we present the unique case of a 7-year-old girl diagnosed with juvenile myelomonocytic leukemia (JMML) and intestinal BD. The patient received allogeneic hematopoietic stem cell transplantation (allo-HSCT), which resulted in complete remission of both JMML and BD. Our findings suggest that allo-HSCT may be a feasible treatment option for JMML patients with coexisting BD, and holds promise for achieving remission of both illnesses. However, further clinical investigations are needed to validate these findings.
摘要:
Behçet病(BD)是一种罕见的疾病,很少与血液系统恶性肿瘤相关。在这个案例报告中,我们介绍了一名7岁女孩的独特病例,该女孩被诊断患有幼年型粒单核细胞白血病(JMML)和肠道BD。患者接受异基因造血干细胞移植(allo-HSCT),这导致了JMML和BD的完全缓解。我们的研究结果表明,allo-HSCT可能是一种可行的治疗选择JMML患者共存的BD,并有望缓解这两种疾病。然而,需要进一步的临床研究来验证这些发现.
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