PDF(Pubmed)
Abstract：
Salmonella Infantis is one of the most frequent serovars reported in broilers and is also regularly identified in human salmonellosis cases, representing a relevant public health problem. In the laboratories of the Istituto Zooprofilattico Sperimentale della Puglia e della Basilicata (IZSPB), six Salmonella Infantis strains with antigenic formula -:r:1,5 have been isolated from the litter and carcass of broilers between 2018 and 2022. The strains were investigated to evaluate their phenotype, antibiotic resistance and genomic profiles. Genomic analysis confirmed that the isolates belonged to the Infantis serotype and to the sequence type ST32. Moreover, all strains showed a multidrug-resistant (MDR) profile and were characterised by the presence of the IncFIB plasmid incompatibility group. Three strains had the blaCTX-M-1 gene, and one of them carried IncX1. The presence of this new variant of S. Infantis is particularly relevant because it could expand the landscape of the S. Infantis population. The absence of the somatic antigen could pose a problem in both isolation and serotyping and a consequent public health concern due to the spread of Salmonella infection.
摘要：
婴儿沙门氏菌是肉鸡中报告的最常见的血清型之一，在人类沙门氏菌病病例中也经常被发现。代表相关的公共卫生问题。在IstitutoZooprofilatticoSperimentaledellaedellaBasilicata（IZSPB）的实验室中，在2018年至2022年之间，已从肉鸡的凋落物和car体中分离出六种具有抗原配方的婴儿沙门氏菌菌株-：r：1,5。对菌株进行了研究以评估其表型，抗生素耐药性和基因组谱。基因组分析证实分离物属于Infantis血清型和序列型ST32。此外，所有菌株均显示多药耐药(MDR)谱,其特征在于存在IncFIB质粒不相容组.三个菌株具有blaCTX-M-1基因，其中一人携带了IncX1。这种新的S.Infantis变体的存在特别相关，因为它可以扩大S.Infantis种群的景观。由于沙门氏菌感染的传播，体细胞抗原的缺乏可能会在分离和血清分型方面造成问题，并因此引起公共卫生问题。
